Browsing by Subject "carcinogen"
Now showing items 1-3 of 3
-
Article
Evidence that a metabolilte of equine estrogens, 4-hydroxyequilenin, induces cellular transformation in vitro
(2001)Estrogen replacement therapy has been correlated with an increased risk of developing hormone-dependent cancers. 4-Hydroxyequilenin (4-OHEN) is a catechol metabolite of equilenin and equilin which are components of the ...
-
Article
Human papillomavirus type 16 E6 and E7 oncoproteins act synergistically to cause head and neck cancer in mice
(2010)High-risk human papillomaviruses (HPVs) contribute to cervical and other anogenital cancers, and they are also linked etiologically to a subset of head and neck squamous cell carcinomas (HNSCC). We previously established ...
-
Article
Identification of biomarkers that distinguish human papillomavirus (HPV)-positive versus HPV-negative head and neck cancers in a mouse model
(2006)Head and neck squamous cell carcinoma (HNSCC) is a leading cause of cancer mortality worldwide. Recent reports have associated a subset of HNSCC with high-risk human papillomaviruses (HPVs), particularly HPV16, the same ...