Browsing by Subject "complement inhibitor"
Now showing items 1-2 of 2
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Article
New compstatin peptides containing n-terminal extensions and non-natural amino acids exhibit potent complement inhibition and improved solubility characteristics
(2015)Compstatin peptides are complement inhibitors that bind and inhibit cleavage of complement C3. Peptide binding is enhanced by hydrophobic interactions
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Article
Species specificity of the complement inhibitor compstatin investigated by all-atom molecular dynamics simulations
(2010)The development of compounds to regulate the activation of the complement system in non-primate species is of profound interest because it can provide models for human diseases. The peptide compstatin inhibits protein C3 ...