Browsing by Subject "drug blood level"
Now showing items 1-3 of 3
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Article
Development of a capillary electrophoresis-mass spectrometry method for the determination of rivastigmine in human plasma - Optimization of the limits of detection and quantitation
(2012)A capillary zone electrophoresis-electrospray ionization-mass spectrometry (CZE-ESI-MS) method was developed for the analysis of the acetylcholinesterase inhibitor rivastigmine. Several electrophoretic and ESI-MS parameters ...
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Article
Model-based tumor growth dynamics and therapy response in a mouse model of de novo carcinogenesis
(2015)Tumorigenesis is a complex, multistep process that depends on numerous alterations within the cell and contribution from the surrounding stroma. The ability to model macroscopic tumor evolution with high fidelity may ...
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Article
Therapeutic monitoring of continuous infusion etoposide in small-cell lung cancer
(1996)Purpose: To investigate the feasibility of therapeutic monitoring of etoposide at different plasma concentrations of the drug, and the resulting pharmacodynamic effects of such an approach. Patients and Methods: Forty- ...