• Article  

      Biphasic modeling of brain tumor biomechanics and response to radiation treatment 

      Angeli, S.; Stylianopoulos, T. (2016)
      Biomechanical forces are central in tumor progression and response to treatment. This becomes more important in brain cancers where tumors are surrounded by tissues with different mechanical properties. Existing mathematical ...
    • Article  

      Evolution of osmotic pressure in solid tumors 

      Voutouri, C.; Stylianopoulos, T. (2014)
      The mechanical microenvironment of solid tumors includes both fluid and solid stresses. These stresses play a crucial role in cancer progression and treatment and have been analyzed rigorously both mathematically and ...
    • Article  

      The role of mechanical forces in tumor growth and therapy 

      Jain, R. K.; Martin, J. D.; Stylianopoulos, T. (2014)
      Tumors generate physical forces during growth and progression. These physical forces are able to compress blood and lymphatic vessels, reducing perfusion rates and creating hypoxia. When exerted directly on cancer cells, ...