• Article  

      High-resolution whole-mount in situ hybridization using quantum dot nanocrystals 

      Ioannou, Androulla; Eleftheriou, Iro; Lubatti, Andrea; Charalambous, Anna; Skourides, Paris A. (2012)
      The photostability and narrow emission spectra of nanometer-scale semiconductor crystallites (QDs) make them desirable candidates for whole-mount fluorescent in situ hybridization to detect mRNA transcripts in morphologically ...
    • Article  

      In vivo imaging of quantum dots encapsulated in phospholipid micelles 

      Dubertret, B.; Skourides, Paris A.; Norris, D. J.; Brivanlou, A. H.; Libchaber, A.; Noireaux, V. (2002)
      Fluorescent semiconductor nanocrystals (quantum dots) have the potential to revolutionize biological imaging, but their use has been limited by difficulties in obtaining nanocrystals that are biocompatible. To address this ...
    • Article  

      Interaction of metal complexes with G-quadruplex DNA 

      Georgiades, Savvas N.; Abd Karim, N. H.; Suntharalingam, K.; Vilar, R. (2010)
      [Figure Presented] Guanine-rich sequences of DNA can assemble into tetrastranded structures known as G-quadruplexes. It has been suggested that these secondary DNA structures could be involved in the regulation of several ...
    • Article  

      Single-shot optical sectioning using two-color probes in HiLo fluorescence microscopy 

      Muro, E.; Vermeulen, P.; Ioannou, Androulla; Skourides, Paris A.; Dubertret, B.; Fragola, A.; Loriette, V. (2011)
      We describe a wide-field fluorescence microscope setup which combines HiLo microscopy technique with the use of a two-color fluorescent probe. It allows one-shot fluorescence optical sectioning of thick biological moving ...