Browsing by Subject "gene location"

Article

Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylation

Kirmizis, Antonis; Santos-Rosa, H.; Penkett, C. J.; Singer, M. A.; Vermeulen, M.; Mann, M.; Bähler, J.; Green, R. D.; Kouzarides, T. (2007)

Modifications on histones control important biological processes through their effects on chromatin structure. Methylation at lysine 4 on histone H3 (H3K4) is found at the 5′ end of active genes and contributes to ...

Article

Authors' reply

Constantinou-Deltas, Constantinos D.; Voskarides, Konstantinos (2010)

Article

Autosomal dominant medullary cystic kidney disease: Evidence of gene locus heterogeneity

Fuchshuber, A.; Constantinou-Deltas, Constantinos D.; Berthold, S.; Stavrou, Christoforos V.; Vollmer, M.; Burton, C.; Feest, T.; Krieter, D.; Gal, A.; Brandis, M.; Pierides, Alkis M.; Hildebrandt, F. (1998)

Autosomal dominant medullary cystic kidney disease (ADMCKD

Article

Chromosome 4 localization of a second gene for autosomal dominant polycystic kidney disease

Peters, D. J. M.; Spruit, L.; Saris, J. J.; Ravine, D.; Sandkuijl, L. A.; Fossdal, R.; Boersma, J.; van Eijk, R.; Nørby, S.; Constantinou-Deltas, Constantinos D.; Pierides, Alkis M.; Briessenden, J. E.; Frants, R. R.; van Ommen, G. -J B.; Breuning, M. H. (1993)

Autosomal dominant polycystic kidney disease (ADPKD) is a genetically heterogeneous disorder. A gene defect located on the short arm of chromosome 16 is responsible for the disease in roughly 86% of affected European ...

Article

CNVs-microRNAs interactions demonstrate unique characteristics in the human genome. An interspecies in silico analysis

Dweep, H.; Georgiou, G. D.; Gretz, N.; Constantinou-Deltas, Constantinos D.; Voskarides, Konstantinos; Felekkis, Kyriacos N. (2013)

MicroRNAs (miRNAs) and copy number variations (CNVs) represent two classes of newly discovered genomic elements that were shown to contribute to genome plasticity and evolution. Recent studies demonstrated that miRNAs and ...

Article

Non-isotopic RNase cleavage assay for mutation detection in MEFV, the gene responsible for familial Mediterranean fever, in a cohort of Greek patients

Ritis, K.; Giaglis, Stavros; Spathari, N.; Micheli, A.; Zonios, D.; Tzoanopoulos, D.; Constantinou-Deltas, Constantinos D.; Rafail, S.; Mean, R.; Papadopoulos, Vassilios P.; Tzioufas, A. G.; Moutsopoulos, H. M.; Kartalis, G. (2004)

Background: The MEFV gene is responsible for familial Mediterranean fever (FMF). Several disease associated mutations have been identified. The range of genetic variation in MEFV in Greek patients has not been determined. ...