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Browsing by Subject "high performance liquid chromatography"

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    • Article  

      Chemometric characterization of the cypriot spirit "Zivania" 

      Kokkinofta, Rebecca I.; Theocharis, Charis R. (2005)
      In 42 alcoholic beverages produced in Cyprus and other countries, 26 chemical and physical-chemical variables were determined by HPLC and GC chromatography, 1H NMR and ICP spectroscopy, and other techniques. Data were ...

    • Article  

      Chiral ionic liquids in chromatographic and electrophoretic separations 

      Kapnissi‐Christodoulou, Constantina P.; Stavrou, Ioannis J.; Mavroudi, Maria C. (2014)
      This report provides an overview of the application of chiral ionic liquids (CILs) in separation technology, and particularly in capillary electrophoresis and both gas and liquid chromatography. There is a large number of ...

    • Article  

      Identification, Distribution and Physiological Activity of Three Novel Neuropeptides of Lymnaea: FLRlamide and pQFYRlamide Encoded by the FMRFamide Gene, and a Related Peptide 

      Santama, Niovi; Wheeler, C. H.; Skingsley, D. R.; Yeoman, M. S.; Bright, K.; Kaye, I.; Burke, J. F.; Benjamin, P. R. (1995)
      We are interested in analysing the detailed modulation of defined neuronal systems by multiple neuropeptides encoded in the FMRFamide locus of the snail Lymnaea. Cloning of the FMRFamide gene has predicted the existence ...

    • Article  

      New compstatin peptides containing n-terminal extensions and non-natural amino acids exhibit potent complement inhibition and improved solubility characteristics 

      Gorham, R. D.; Forest, D. L.; Khoury, G. A.; Smadbeck, J.; Beecher, C. N.; Healy, E. D.; Tamamis, Phanourios; Archontis, Georgios Z.; Larive, C. K.; Floudas, C. A.; Radeke, M. J.; Johnson, L. V.; Morikis, D. (2015)
      Compstatin peptides are complement inhibitors that bind and inhibit cleavage of complement C3. Peptide binding is enhanced by hydrophobic interactions

    • Article  

      Novel approach to fast determination of cholesterol oxidation products in Cypriot foodstuffs using ultra-performance liquid chromatography-tandem mass spectrometry 

      Georgiou, Christiana A.; Constantinou, Michalis S.; Andreou, Rafaella; Hapeshi, Evroula; Fatta‐Kassinos, Despo; Kapnissi‐Christodoulou, Constantina P. (2016)
      This paper reports the development and validation of a new method based on ultra-performance LC coupled to MS/MS for the simultaneous determination of four cholesterol oxidation products (COPs) in foodstuffs in only 4.1 ...

    • Article  

      Novel compstatin family peptides inhibit complement activation by drusen-like deposits in human retinal pigmented epithelial cell cultures 

      Gorham, R. D.; Forest, D. L.; Tamamis, Phanourios; López de Victoria, A.; Kraszni, M.; Kieslich, C. A.; Banna, C. D.; Bellows-Peterson, M. L.; Larive, C. K.; Floudas, C. A.; Archontis, Georgios Z.; Johnson, L. V.; Morikis, D. (2013)
      We have used a novel human retinal pigmented epithelial (RPE) cell-based model that mimics drusen biogenesis and the pathobiology of age-related macular degeneration to evaluate the efficacy of newly designed peptide ...

    • Article  

      Qualitative and quantitative determination of COPs in cypriot meat samples using HPLC determination of the most effective sample preparation procedure 

      Georgiou, Christiana A.; Kapnissi‐Christodoulou, Constantina P. (2013)
      This research work describes the development of a fast high-performance liquid chromatography method for the simultaneous determination of five important cholesterol oxidation products (COPs). The influence of various ...

    • Article  

      Sample preparation: A critical step in the analysis of cholesterol oxidation products 

      Georgiou, Christiana A.; Constantinou, Michalis S.; Kapnissi‐Christodoulou, Constantina P. (2014)
      In recent years, cholesterol oxidation products (COPs) have drawn scientific interest, particularly due to their implications on human health. A big number of these compounds have been demonstrated to be cytotoxic, mutagenic, ...

    • Article  

      Separation of benzodiazepines using capillary electrochromatography 

      Kapnissi‐Christodoulou, Constantina P.; Warner, I. M. (2004)
      Benzodiazepines are often used for the treatment of epilepsy, convulsions, and many psychiatric disorders. The widespread use of this class of drugs has occasionally raised concern about recreational benzodiazepine abuse ...

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