Browsing by Subject "human"
Now showing items 1-20 of 460
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The 1.76 Å resolution crystal structure of glycogen phosphorylase b complexed with glucose, and CP320626, a potential antidiabetic drug
(2002)CP320626, a potential antidiabetic drug, inhibits glycogen phosphorylase in synergism with glucose. To elucidate the structural basis of synergistic inhibition, we determined the structure of muscle glycogen phosphorylase ...
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2nd combined working group and management committee meeting of urine and kidney proteomics COST action 29-30 March 2009, Nafplio, Greece
(2009)EuroKUP (Urine and Kidney Proteomics
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The A and B fragments of normal type I procollagen have a similar thermal stability to proteinase digestion but are selectively destabilized by structural mutations
(1987)Previous studies demonstrated that the thermal stability of the procollagen triple helix can be assayed by digesting the protein for short periods with high concentrations of trypsin and chymotrypsin. Here we cleaved human ...
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A ligand-independent integrin β1 mechanosensory complex guides spindle orientation
(2016)Control of spindle orientation is a fundamental process for embryonic development, morphogenesis and tissue homeostasis, while defects are associated with tumorigenesis and other diseases. Force sensing is one of the ...
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Conference Object
Adaptive emergency scenery video communications using HEVC for responsive decision support in disaster incidents
(Institute of Electrical and Electronics Engineers Inc., 2015)This study proposes a unifying framework for m-Health video communication systems that provides for the joint optimization of video quality, bitrate demands, and encoding time. The framework is video modality and infrastructure ...
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Algorithmic mechanisms for reliable crowdsourcing computation under collusion
(2015)We consider a computing system where a master processor assigns a task for execution to worker processors that may collude. We model the workers' decision of whether to comply (compute the task) or not (return a bogus ...
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Allele distribution of 15 STR loci used for human identity purposes in the Greek Cypriot population of the island of Cyprus
(2006)Allele frequencies for 15 STRs (D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, THO1, Penta E, D16S539, CSF1PO, Penta D and TPOX) in the PowerPlex®-16 System (Promega Corporation) were derived from a ...
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Alport syndrome from bench to bedside: The potential of current treatment beyond RAAS blockade and the horizon of future therapies
(2014)The hereditary type IV collagen disease Alport syndrome (AS) always leads to end-stage renal failure. Yesterday, for the past 90 years, this course was described as 'inevitable'. Today, RAAS blockade has changed the ...
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Altered Phosphorylation, Biosynthesis and Degradation of the 170 kDa Isoform of Topoisomerase II in Amsacrine-Resistant Human Leukemia Cells
(1993)Resistance to amsacrine in HL-60/AMSA is 50-100 fold compared to the parental HL-60/S cells. Synthesis and phosphorylation of topoisomerase II (TOPO II) were 2-3 fold lower in HL-60/AMSA compared to HL-60/S cells metabolically ...
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AM-FM texture segmentation in electron microscopic muscle imaging
(2000)This paper describes the application of an amplitude modulation-frequency modulation (AM-FM) image representation in segmenting electron micrographs of skeletal muscle for the recognition of: 1) normal sarcomere ultrastructural ...
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Analysis of expired air of fasting male monks at Mount Athos
(2006)Expired air chemical analysis is investigated as a search and locate method for the early detection of entrapped people under the ruins of collapsed buildings after an earthquake. Fasting individuals were examined as a ...
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Analysis of volatile organic compounds released from the decay of surrogate human models simulating victims of collapsed buildings by thermal desorption-comprehensive two-dimensional gas chromatography-time of flight mass spectrometry
(2015)Field experiments were devised to mimic the entrapment conditions under the rubble of collapsed buildings aiming to investigate the evolution of volatile organic compounds (VOCs) during the early dead body decomposition ...
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Application of ion mobility spectrometry for the detection of human urine
(2010)The aim of the present study was to evaluate the suitability of ion mobility spectrometry (IMS) for the detection of human urine as an indication of human presence during urban search and rescue operations in collapsed ...
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Architectural insight into inovirus-associated vectors (IAVs) and development of IAV-based vaccines inducing humoral and cellular responses: Implications in HIV-1 vaccines
(2014)Inovirus-associated vectors (IAVs) are engineered, non-lytic, filamentous bacteriophages that are assembled primarily from thousands of copies of the major coat protein gp8 and just five copies of each of the four minor ...
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Assessment of the risk factors of coronary heart events based on data mining with decision trees
(2010)Coronary heart disease (CHD) is one of the major causes of disability in adults as well as one of the main causes of death in the developed countries. Although significant progress has been made in the diagnosis and treatment ...
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Association rule analysis for the assessment of the risk of coronary heart events.
(2009)Although significant progress has been made in the diagnosis and treatment of coronary heart disease (CHD), further investigation is still needed. The objective of this study was to develop a data mining system using ...
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Atherosclerotic plaque ultrasound video encoding, wireless transmission, and quality assessment using H.264
(2011)We propose a unifying framework for efficient encoding, transmission, and quality assessment of atherosclerotic plaque ultrasound video. The approach is based on a spatially varying encoding scheme, where video-slice ...
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Attenuation of drug-stimulated topoisomerase II-DNA cleavable complex formation in wild-type HL-60 cells treated with an intracellular calcium buffer is correlated with decreased cytotoxicity and site-specific hypophosphorylation of topoisomerase IIα
(1998)Topoisomerase II (topo II), an essential enzyme for cell viability, is also the target for clinically important anti-neoplastic agents that stimulate topo II-mediated DNA scission. The role of alterations in topo IIα ...
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Authors' reply
(2010)