• Article  

      Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylation 

      Kirmizis, Antonis; Santos-Rosa, H.; Penkett, C. J.; Singer, M. A.; Vermeulen, M.; Mann, M.; Bähler, J.; Green, R. D.; Kouzarides, T. (2007)
      Modifications on histones control important biological processes through their effects on chromatin structure. Methylation at lysine 4 on histone H3 (H3K4) is found at the 5′ end of active genes and contributes to ...
    • Article  

      Drosophila and the hallmarks of cancer 

      Christofi, T.; Apidianakis, Yiorgos (2013)
      : Cancer was the disease of the twentieth century. Today it is still a leading cause of death worldwide despite being intensively investigated. Abundant knowledge exists regarding the pathological and molecular mechanisms ...
    • Article  

      Spatially and temporally regulated α6 integrin cleavage during Xenopus laevis development 

      Demetriou, Manolis C.; Stylianou, Panayiota; Andreou, Maria I.; Yiannikouri, Olga; Tsaprailis, George; Cress, Anne E.; Skourides, Paris A. (2008)
      The α6 integrin is essential for early nervous system development in Xenopus laevis. We have previously reported a uPA cleaved form of integrin α6 (α6p), in invasive human prostate cancer tissue, whose presence correlates ...