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Browsing by Subject "mathematical model"

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    • Article  

      Algorithmic mechanisms for reliable crowdsourcing computation under collusion 

      Fernández Anta, Antonio; Georgiou, Chryssis; Mosteiro, Miguel A.; Pareja, D. (2015)
      We consider a computing system where a master processor assigns a task for execution to worker processors that may collude. We model the workers' decision of whether to comply (compute the task) or not (return a bogus ...

    • Article  

      A Biophysical Model of Endocannabinoid-Mediated Short Term Depression in Hippocampal Inhibition 

      Zachariou, Margarita; Alexander, S. P. H.; Coombes, S.; Christodoulou, Chris C. (2013)
      Memories are believed to be represented in the synaptic pathways of vastly interconnected networks of neurons. The plasticity of synapses, that is, their strengthening and weakening depending on neuronal activity, is ...

    • Article  

      A biophysical model of endocannabinoidmediated short term depression of excitation in hippocampus 

      Zachariou, Margarita; Christodoulou, Chris C. (2013)

    • Article  

      Coefficient of variation vs. mean interspike interval curves: What do they tell use about the brain? 

      Christodoulou, Chris C.; Bugmann, G. (2001)
      A number of models have been produced recently to explain the high variability of natural spike trains (Softky and Koch, J. Neurosci. 13 (1) (1993) 334). These models use a range of different biological mechanisms including ...

    • Article  

      Coevolution of solid stress and interstitial fluid pressure in tumors during progression: Implications for vascular collapse 

      Stylianopoulos, T.; Martin, J. D.; Snuderl, M.; Mpekris, F.; Jain, S. R.; Jain, R. K. (2013)
      The stress harbored by the solid phase of tumors is known as solid stress. Solid stress can be either applied externally by the surrounding normal tissue or induced by the tumor itself due to its growth. Fluid pressure is ...

    • Article  

      The effect of strain hardening on the dynamic response of human artery segments 

      Charalambous, H. P.; Roussis, Panayiotis C.; Giannakopoulos, A. E. (2017)
      Background: When subjected to time-dependent blood pressure, human arteries undergo large deformations, exhibiting mainly nonlinear hyperelastic type of response. The mechanical response of arteries depends on the health ...

    • Article  

      Effect of zooming on texture features of ultrasonic images 

      Kakkos, Stavros K.; Nicolaïdes, Andrew N.; Kyriacou, Efthyvoulos C.; Pattichis, Constantinos S.; Geroulakos, George (2006)
      Background: Unstable carotid plaques on subjective, visual, assessment using B-mode ultrasound scanning appear as echolucent and heterogeneous. Although previous studies on computer assisted plaque characterisation have ...

    • Article  

      Evolution of osmotic pressure in solid tumors 

      Voutouri, C.; Stylianopoulos, T. (2014)
      The mechanical microenvironment of solid tumors includes both fluid and solid stresses. These stresses play a crucial role in cancer progression and treatment and have been analyzed rigorously both mathematically and ...

    • Article  

      The evolutionary consequences of interspecific aggression 

      Grether, G. F.; Anderson, Christopher N.; Drury, J. P.; Kirschel, A. N. G.; Losin, N.; Okamoto, K.; Peiman, K. S. (2013)
      Competition has always been a cornerstone of evolutionary biology, and aggression is the predominant form of direct competition in animals, but the evolutionary effects of aggression between species are curiously understudied. ...

    • Article  

      Experimental measurements and mathematical modeling towards quantification of brain swelling stress 

      Angeli, S.; Stylianopoulos, T. (2017)
      Traumatic brain injury results in brain tissue swelling which can be a life threatening condition due to skull confinement. While previous efforts successfully measured the exhibited volume change in brain tissue swelling, ...

    • Article  

      Fabrication of nanocrystalline Mg 2Si via ball milling process: Structural studies 

      Ioannou, M.; Hatzikraniotis, E.; Lioutas, C.; Hassapis, T.; Altantzis, T.; Paraskevopoulos, K. M.; Kyratsi, Theodora (2012)
      In this work, nanocrystalline Mg 2Si material was fabricated via wet ball milling process using n-hexane as process control agent. Milling parameters, with emphasis on milling time and ball size, and conditions were studied ...

    • Article  

      First Trimester Noninvasive Prenatal Diagnosis: A Computational Intelligence Approach 

      Neocleous, Andreas C.; Nicolaides, Kypros H.; Schizas, Christos N. (2016)
      The objective of this study is to examine the potential value of using machine learning techniques such as artificial neural network (ANN) schemes for the noninvasive estimation, at 11-13 weeks of gestation, the risk for ...

    • Article  

      Hyaluronan-Derived Swelling of Solid Tumors, the Contribution of Collagen and Cancer Cells, and Implications for Cancer Therapy 

      Voutouri, C.; Polydorou, C.; Papageorgis, P.; Gkretsi, V.; Stylianopoulos, T. (2016)
      Despite the important role that mechanical forces play in tumor growth and therapy, the contribution of swelling to tumor mechanopathology remains unexplored. Tumors rich in hyaluronan exhibit a highly negative fixed charge ...

    • Article  

      Implications of HIV-1 M group polymorphisms on integrase inhibitor efficacy and resistance: Genetic and structural in silico analyses 

      Loizidou, Eriketi Z.; Kousiappa, Ioanna; Zeinalipour-Yazdi, Constantinos D.; Van De Vijver, D. A. M. C.; Kostrikis, Leontios G. (2009)
      The extensive polymorphisms among HIV-1 subtypes have been implicated in drug resistance development. Integrase inhibitors represent the latest addition to the treatment of HIV-1, and their efficacy and resistance patterns ...

    • Article  

      Implications of HIV-1 M group polymorphisms on integrase inhibitor efficacy and resistance: Genetic and structural in silico analyses 

      Loizidou, Eriketi Z.; Kousiappa, Ioanna; Zeinalipour-Yazdi, Constantinos D.; Van De Vijver, D. A. M. C.; Kostrikis, Leontios G. (2009)
      The extensive polymorphisms among HIV-1 subtypes have been implicated in drug resistance development. Integrase inhibitors represent the latest addition to the treatment of HIV-1, and their efficacy and resistance patterns ...

    • Article  

      In silico assessment of mouth-throat effects on regional deposition in the upper tracheobronchial airways 

      Koullapis, P. G.; Nicolaou, L.; Kassinos, Stavros C. (2018)
      Regional deposition of inhaled medicines is a valuable metric of effectiveness in drug delivery applications to the lung. In silico methods are now emerging as a valuable tool for the detailed description of localized ...

    • Article  

      Lattice free energy with overlap fermions: A two-loop result 

      Athenodorou, A.; Panagopoulos, Haralambos G. (2004)
      We calculate the two-loop partition function of QCD on the lattice, using the Wilson formulation for gluons and the overlap-Dirac operator for fermions. Direct by-products of our result are the two-loop free energy and ...

    • Article  

      Mathematical modeling of herpes simplex virus distribution in solid tumors: Implications for cancer gene therapy 

      Mok, W.; Stylianopoulos, T.; Boucher, Y.; Jain, R. K. (2009)
      Purpose: Although oncolytic viral vectors show promise for the treatment of various cancers, ineffective initial distribution and propagation throughout the tumor mass often limit the therapeutic response. A mathematical ...

    • Article  

      Mathematical modeling of the oxygen storage capacity phenomenon studied by CO pulse transient experiments over Pd/CeO2 catalyst 

      Costa, Costas N.; Christou, Stavroula Y.; Georgiou, Georgios C.; Efstathiou, Angelos M. (2003)
      A mathematical model has been developed for the first time to study the oxygen storage capacity (OSC) phenomenon by the CO pulse injection technique over a 1 wt% Pd/CeO2 model catalyst in the 500-700°C range. A two-step ...

    • Article  

      Mathematical modeling of the oxygen storage capacity phenomenon studied by CO pulse transient experiments over Pd/CeO2 catalystAAA 

      Costa, Costas N.; Christou, Stavroula Y.; Georgiou, Georgios C.; Efstathiou, Angelos M. (2003)
      A mathematical model has been developed for the first time to study the oxygen storage capacity (OSC) phenomenon by the CO pulse injection technique over a 1 wt% Pd/CeO2 model catalyst in the 500-700°C range. A two-step ...

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