Browsing by Subject "physiology"

Article

40LoVe and Samba are involved in Xenopusneural development and functionally distinct from hnRNP AB

Andreou, Maria I.; Yan, C. Y. I.; Skourides, Paris A. (2014)

Heterogeneous nuclear ribonucleoproteins (hnRNPs) comprise a large group of modular RNA-binding proteins classified according to their conserved domains. This modular nature, coupled with a large choice of alternative ...

Article

Acoustic localization of antbirds in a Mexican rainforest using a wireless sensor network

Collier, T. C.; Kirschel, A. N. G.; Taylor, C. E. (2010)

Acoustic localization is a promising method to passively observe vocal animal species, but remains difficult and time consuming to employ. To reduce the labor intensity and impact of deployment, an acoustic localization ...

Article

The bacterial metabolite 2-aminoacetophenone promotes association of pathogenic bacteria with flies

Kapsetaki, Stefania Elisavet; Tzelepis, Ilias; Avgousti, Kalodoti; Livadaras, Ioannis; Garantonakis, Nikos G.; Varikou, Kyriaki N.; Apidianakis, Yiorgos (2014)

Bacteria contaminate insects and secrete metabolites that may affect insect behaviour and potentially fitness through unknown mechanisms. Here we show that the 'grape-like' odorant 2-aminoacetophenone (2AA), secreted by ...

Article

Balanced translocations for the analysis of imprinted regions of the mouse genome.

Ferguson-Smith, A. C.; Tevendale, M.; Georgiades, Pantelis; Grandjean, V. (2001)

Experimental studies that investigate the functional and mechanistic properties of an imprinted locus require material in which the two parental chromosome homologs can be easily distinguished. The use of animals with ...

Article

Cell-Autonomous Ca(2+) Flashes Elicit Pulsed Contractions of an Apical Actin Network to Drive Apical Constriction during Neural Tube Closure

Christodoulou, Neophytos; Skourides, Paris A. (2015)

Neurulation is a critical period in all vertebrates and results in the formation of the neural tube, which gives rise to the CNS. Apical constriction is one of the fundamental morphogenetic movements that drives neural ...

Article

Combination of theoretical and experimental approaches for the design and study of fibril-forming peptides

Tamamis, Phanourios; Kasotakis, E.; Archontis, Georgios Z.; Mitraki, A. (2014)

Self-assembling peptides that can form supramolecular structures such as fibrils, ribbons, and nanotubes are of particular interest to modern bionanotechnology and materials science. Their ability to form biocompatible ...

Article

Comparing Different Classifiers for Automatic Age Estimation

Lanitis, A.; Draganova, C.; Christodoulou, Chris C. (2004)

We describe a quantitative evaluation of the performance of different classifiers in the task of automatic age estimation. In this context, we generate a statistical model of facial appearance, which is subsequently used ...

Article

Cystic diseases of the kidney molecular biology and genetics

Constantinou-Deltas, Constantinos D. (2010)

Context.-Cystic diseases of the kidney are a very heterogeneous group of renal inherited conditions, with more than 33 genes involved and encompassing Xlinked, autosomal dominant, and autosomal recessive inheritance. ...

Article

Depletion of histone N-terminal-acetyltransferase Naa40 induces p53-independent apoptosis in colorectal cancer cells via the mitochondrial pathway

Pavlou, Demos; Kirmizis, Antonis (2016)

Protein N-terminal acetylation is an abundant post-translational modification in eukaryotes implicated in various fundamental cellular and biochemical processes. This modification is catalysed by evolutionarily conserved ...

Article

Distinguishing the causes of firing with themembrane potential slope

Koutsou, Achilleas; Christodoulou, Chris C.; Bugmann, G.; Kanev, J. (2012)

In this letter, we aim to measure the relative contribution of coincidence detection and temporal integration to the firing of spikes of a simple neuron model. To this end, we develop a method to infer the degree of synchrony ...

Article

Does high firing irregularity enhance learning?

Christodoulou, Chris C.; Cleanthous, A. (2011)

In this note, we demonstrate that the high firing irregularity produced by the leaky integrate-and-fire neuron with the partial somatic reset mechanism, which has been shown to be the most likely candidate to reflect the ...

Article

Editorial

Lucas, P.; Rospars, J. -P; Christodoulou, Chris C. (2015)

Article

Effect of head posture on the healthy human carotid bifurcation hemodynamics

Papaharilaou, Yannis; Aristokleous, Nicolas; Seimenis, Ioannis; Khozeymeh, M. I.; Georgiou, Georgios C.; Brott, B. C.; Eracleous, Eleni A.; Anayiotos, Andreas S. (2013)

Head and neck postures may cause morphology changes to the geometry of the carotid bifurcation (CB) that alter the low and oscillating wall shear stress (WSS) regions previously reported as important in the development of ...

Article

The Effect of Head Rotation on the Geometry and Hemodynamics of Healthy Vertebral Arteries

Aristokleous, Nicolas; Seimenis, Ioannis; Georgiou, Georgios C.; Nicolaïdes, Andrew N.; Anayiotos, Andreas S. (2015)

The geometric and hemodynamic characteristics of the left and right vertebral arteries (LVA, RVA) of six healthy volunteers were investigated for the supine (S) and the prone position (P) a common sleeping posture with ...

Article

Effect of posture change on the geometric features of the healthy carotid bifurcation

Aristokleous, Nicolas; Seimenis, Ioannis; Papaharilaou, Yannis; Georgiou, Georgios C.; Brott, B. C.; Eracleous, Eleni A.; Anayiotos, Andreas S. (2011)

Segmented cross-sectional MRI images were used to construct 3-D virtual models of the carotid bifurcation in ten healthy volunteers. Geometric features, such as bifurcation angle, internal carotid artery (ICA) angle, ...

Article

Electron transfer mechanisms

Beratan, David N.; Skourtis, Spiros S. (1998)

The tunneling pathway framework description of protein electron transfer reactions has prompted a lively discussion of how structure and evolution influence electron transfer rates. Recent protein and model system experiments, ...

Article

An embedded saliency map estimator scheme: Application to video encoding

Tsapatsoulis, Nicolas; Rapantzikos, K.; Pattichis, Constantinos S. (2007)

In this paper we propose a novel saliency-based computational model for visual attention. This model processes both top-down (goal directed) and bottom-up information. Processing in the top-down channel creates the so ...

Article

Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms

Liu, J.; Burdette, J. E.; Xu, H.; Gu, C.; Van Breemen, R. B.; Bhat, K. P. L.; Booth, N.; Constantinou, Andreas I.; Pezzuto, J. M.; Fong, H. H. S.; Farnsworth, N. R.; Bolton, J. L. (2001)

Eight botanical preparations that are commonly used for the treatment of menopausal symptoms were tested for estrogenic activity. Methanol extracts of red clover (Trifolium pratense L.), chasteberry (Vitex agnus-castus ...

Article

Evolution of osmotic pressure in solid tumors

Voutouri, C.; Stylianopoulos, T. (2014)

The mechanical microenvironment of solid tumors includes both fluid and solid stresses. These stresses play a crucial role in cancer progression and treatment and have been analyzed rigorously both mathematically and ...

Article

FAK transduces extracellular forces that orient the mitotic spindle and control tissue morphogenesis

Petridou, Nicoletta I.; Skourides, Paris A. (2014)

Spindle orientation is critical for proper morphogenesis of organs and tissues as well as for the maintenance of tissue morphology. Although significant progress has been made in understanding the mechanisms linking the ...