Browsing by Subject "pressure gradient"
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Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner (2012)The blood vessels of cancerous tumours are leaky and poorly organized. This can increase the interstitial fluid pressure inside tumours and reduce blood supply to them, which impairs drug delivery. Anti-angiogenic ...
Regional aerosol deposition in the human airways: The SimInhale benchmark case and a critical assessment of in silico methods (2018)Regional deposition effects are important in the pulmonary delivery of drugs intended for the topical treatment of respiratory ailments. They also play a critical role in the systemic delivery of drugs with limited lung ...