Browsing by Subject "proton nuclear magnetic resonance"

Article

Amphiphilic diblock and ABC triblock methacrylate copolymers: Synthesis and aqueous solution characterization

Triftaridou, Aggeliki I.; Vamvakaki, Maria; Patrickios, Costas S. (2002)

Three isomeric, linear, equimolar, amphiphilic ABC triblock copolymers comprising methyl methacrylate (MMA, nonionic hydrophobic), 2-(dimethylamino)ethyl methacrylate, (DMAEMA, ionizable hydrophilic) and hexa(ethylene ...

Article

Amphiphilic model conetworks based on cross-linked star copolymers of benzyl methacrylate and 2-(dimenthylamino)ethyl methacrylate: Synthesis, characterization, and DNA adsorption studies

Achilleos, Demetra S.; Georgiou, Theoni K.; Patrickios, Costas S. (2006)

Six amphiphilic model conetworks of a new structure, that of cross-linked "in-out" star copolymers, were synthesized by the group transfer polymerization (GTP) of the hydrophobic monomer benzyl methacrylate (BzMA) and the ...

Article

Concerted Diels-Alder reaction between anthracene and C60

Chronakis, Nikos; Orfanopoulos, Michael (2001)

The Diels-Alder reaction of anthracene with C60 has been investigated experimentally by using secondary isotope effects. The inverse α-secondary isotope effect in conjunction with the unity value of the β-secondary isotope ...

Article

Controlled synthesis of homopolymers and block copolymers based on 2-(acetoacetoxy)ethyl methacrylate via RAFT radical polymerisation

Krasia-Christoforou, T.; Soula, R.; Börner, H. G.; Schlaad, H. (2003)

Reversible addition-fragmentation chain transfer (RAFT) radical polymerisation enables to synthesise well-defined homopolymers and block copolymers based on 2-(acetoacetoxy)ethyl methacrylate, which are capable to strongly ...

Article

The conversion of 2-(4-chloro-5H-1,2,3-dithiazolylideneamino)benzonitriles into 3-aminoindole-2-carbonitriles using triphenylphosphine

Michaelidou, Sophia S.; Koutentis, Panayiotis Andreas (2009)

2-(4-Chloro-5H-1,2,3-dithiazolylideneamino)benzonitrile 1a reacts with triphenylphosphine (4 equiv) in the presence of water (2 equiv) to afford anthranilonitrile 2a, 3-aminoindole-2-carbonitrile 3a and (2-cyanoindol-3-y ...

Article

The conversion of 2-cyano cyanothioformanilides into 3-aminoindole-2- carbonitriles using triphenylphosphine

Koutentis, Panayiotis Andreas; Michaelidou, Sophia S. (2010)

2-Cyano cyanothioformanilide 3a reacts with triphenylphosphine in the presence of water to give 2-(cyanomethyleneamino)benzonitrile 4a, 2-(cyanomethylamino)benzonitrile 5, 3-aminoindole-2-carbonitrile 2a and (2-cyanoindo ...

Article

The conversion of isothiazoles into pyrazoles using hydrazine

Ioannidou, Heraklidia A.; Koutentis, Panayiotis Andreas (2009)

The conversion of isothiazoles into pyrazoles on treatment with hydrazine is investigated. The influence of various C-3, C-4 and C-5 isothiazole substituents and some limitations of this ring transformation are examined. ...

Article

Formation of oligotriazoles catalysed by cucurbituril

Krasia-Christoforou, T.; Steinke, J. H. G. (2002)

The catalytic activity of cucurbituril in 1,3-dipolar cycloadditions has been applied to the synthesis of oligotriazoles.

Article

In vivo high-resolution magic angle spinning magnetic resonance spectroscopy of Drosophila melanogaster at 14.1 T shows trauma in aging and in innate immune-deficiency is linked to reduced insulin signaling

Righi, V.; Apidianakis, Yiorgos; Mintzopoulos, D.; Astrakas, L.; Rahme, L. G.; Tzika, A. A. (2010)

In vivo magnetic resonance spectroscopy (MRS), a non-destructive biochemical tool for investigating live organisms, has yet to be used in the fruit fly Drosophila melanogaster, a useful model organism for investigating ...

Article

In vivo high-resolution magic angle spinning proton NMR spectroscopy of Drosophila melanogaster flies as a model system to investigate mitochondrial dysfunction in Drosophila GST2 mutants

Righi, V.; Apidianakis, Yiorgos; Psychogios, N.; Rahme, L. G.; Tompkins, R. G.; Tzika, A. A. (2014)

In vivo nuclear magnetic resonance spectroscopy (NMR), a non-destructive biochemical tool used for investigating live organisms, has recently been performed in studies of the fruit fly Drosophila melanogaster, a useful ...

Article

Inhibition of mitogen-activated protein kinase (MAPK) and cyclin-dependent kinase 2 (Cdk2) by platinum(II) phenanthroline complexes

Child, E. S.; Georgiades, Savvas N.; Rose, K. N.; Stafford, V. S.; Patel, C. B. K.; Steinke, J. H. G.; Mann, D. J.; Vilar, R. (2011)

Inhibition of protein kinases in the fight against disease remains a constant challenge for medicinal chemists, who have screened multitudes of predominantly planar organic scaffolds, natural and synthetic, to identify ...

Article

A new [2 + 2] functionalization of C60 with alkyl-substituted 1,3- butadienes: A mechanistic approach. Stereochemistry and isotope effects

Vassilikogiannakis, G.; Chronakis, Nikos; Orfanopoulos, Michael (1998)

The stereochemistry and secondary isotope effects of the [2 + 2] photocycloaddition of trans,trans- (7), cis,cis- (8), and cis,trans-2,4- hexadiene (9), 2,5-dimethyl-2,4-hexadiene (1), and its deuterated analogues 1-d1, ...

Article

NMR and theoretical investigations on the structures and dynamics of octahedral bis(chelate)dichloro VIII compounds isolated by an unusual reduction of non-oxo VIV species

Rikkou, Maria P.; Manos, Manolis J.; Tolis, Evangelos I.; Sigalas, Michael P.; Kabanos, Themistoklis A.; Keramidas, Anastasios D. (2003)

Reaction of the non-oxo VIV species [VIVCl2(LOO)2] [LOO = acetylacetonate (acac-) or benzoylacetonate (bzac-)] with a chelate nitrogen-donor ligand LNN in acetonitrile leads to the reduction of VIV to VIII and the formation ...

Article

Novel mixed metal Ag(I)-Sb(III)-metallotherapeutics of the NSAIDs, aspirin and salicylic acid: Enhancement of their solubility and bioactivity by using the surfactant CTAB

Gkaniatsou, E. I.; Banti, Christina N.; Kourkoumelis, Nikolaos; Skoulika, S.; Manoli, Maria; Tasiopoulos, Anastasios J.; Hadjikakou, Sotiris K. (2015)

The already known Ag(I)-Sb(III) compound of the formula {Ag(Ph3Sb)3(NO3)} (1) and two novel mixed metal Ag(I)-Sb(III) metallotherapeutics of the formulae {Ag(Ph3Sb)3(SalH)}(2) and {Ag(Ph3Sb)3(Asp)}(3) (SalH2 = salicylic ...

Article

The preparation and characterization of 5-substituted-4-chloro-1,2,3- dithiazolium salts and their conversion into 4-substituted-3-chloro-1,2,5- thiadiazoles

Koutentis, Panayiotis Andreas (2005)

A series of monosubstituted acetonitriles were treated with disulfur dichloride at room temperature in CH2Cl2 to afford 5-substituted-4-chloro-1,2,3-dithiazolium chlorides 1. Where the 5-substituent was not a good leaving ...

Article

Reinvestigating the reaction of 1H-pyrazol-5-amines with 4,5-dichloro-1,2,3-dithiazolium chloride: A route to pyrazolo[3,4-c]isothiazoles and pyrazolo[3,4-d]thiazoles

Koyioni, Maria G.; Manoli, Maria; Manolis, M. J.; Koutentis, Panayiotis Andreas (2014)

The reaction of Appel salt 1 with 1H-pyrazol-5-amines 2 gives main products N-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-1H-pyrazol-5-amines 3, and 6H-pyrazolo[3,4-c]isothiazole-3-carbonitriles 5, together with several minor ...

Article

Reinvestigating the synthesis of N-arylbenzamidines from benzonitriles and anilines in the presence of AlCl3

Koutentis, Panayiotis Andreas; Mirallai, Styliana I. (2010)

The preparation of N-phenylbenzamidine 3a from the reaction between benzonitrile Ia and aniline in the presence of AId3 is reinvestigated with respect to mode of reagent addition, reaction temperature and Lewis acid ...

Article

Ring transformations of 2-hydroxy-(4-chloro-5H-1,2,3-dithiazol-5-ylideneamino)arenes

Kalogirou, Andreas S.; Michaelidou, Sophia S.; Koyioni, Maria G.; Koutentis, Panayiotis Andreas (2015)

Abstract The cyclisation reactions of 2-(4-chloro-5H-1,2,3-dithiazol-5-ylidene-amino)phenol (5a), 3-(4-chloro-5H-1,2,3-dithiazol-5-ylideneamino)pyridin-2-ol (5b) and 2-(4-chloro-5H-1,2,3-dithiazol-5-ylideneamino)pyridin-3-ol ...

Article

Superhelices of poly[2-(acetoacetoxy)ethyl methacrylate]

Schlaad, H.; Krasia-Christoforou, T.; Antonietti, M. (2004)

Poly[2-(acetoacetoxy) ethyl methacrylate] (PAEMA) homopolymers were found to self-assemble into hierarchical superstructures, that is, double-stranded helical tubes of either screw sense (scanning force microscopy). Both ...

Article

Synthesis and aqueous solution characterization of amphiphilic diblock copolymers containing carbazole

Krasia-Christoforou, T.; Patrickios, C. S. (2002)

A series of near-monodisperse diblock copolymers of 2-(N-carbazolyl)ethyl methacrylate and 2-(dimethylamino)ethyl methacrylate (DMAEMA) of relatively low molecular weights (2600-24,000 g mol-1) were synthesized by group ...