Browsing by Subject "rat strain"

Now showing items 1-3 of 3

Article

Chemopreventive effects of soy protein and purified soy isoflavones on DMBA-induced mammary tumors in female Sprague-Dawley rats

Constantinou, Andreas I.; Lantvit, D.; Hawthorne, M.; Xu, X.; Van Breemen, R. B.; Pezzuto, J. M. (2001)

There are conflicting reports on the effect of soy and its components on mammary carcinogenesis in adult female rats, mainly because of different rodent models that are used in chemoprevention studies. The present study ...
Article

Phenoxodiol, a novel isoflavone derivative, inhibits dimethylbenz[a]anthracene (DMBA)-induced mammary carcinogenesis in female Sprague-Dawley rats

Constantinou, Andreas I.; Mehta, R.; Husband, A. (2003)

The present study was undertaken to evaluate the potential cancer chemopreventive effects of novel synthetic derivatives of isoflavones. Initially these agents were tested in a mouse mammary organ culture (MMOC) model. ...
Article

Trifolium pratense (red clover) exhibits estrogenic effects in vivo in ovariectomized sprague-dawley rats

Burdette, J. E.; Liu, J.; Lantvit, D.; Lim, E.; Booth, N.; Bhat, K. P. L.; Hedayat, S.; Van Breemen, R. B.; Constantinou, Andreas I.; Pezzuto, J. M.; Farnsworth, N. R.; Bolton, J. L. (2002)

Studies were conducted using an ovariectomized rat model to determine the estrogenic and antiestrogenic activity of Trifolium pratense L. (red clover) extracts. A red clover extract, standardized to contain 15% isoflavones ...