Browsing by Subject "sensitivity and specificity"

Article

Analysis of polyphenols using capillary zone electrophoresis - Determination of the most effective wine sample pre-treatment method

Nicolaou, I. N.; Kapnissi‐Christodoulou, Constantina P. (2010)

A simple CZE method has been developed for the simultaneous determination of eight polyphenolic compounds. The influence of several experimental conditions such as buffer (concentration and pH) and temperature were studied. ...

Article

Association rule analysis for the assessment of the risk of coronary heart events.

Karaolis, Minas A.; Moutiris, Joseph Antoniou; Papaconstantinou, L.; Pattichis, Constantinos S. (2009)

Although significant progress has been made in the diagnosis and treatment of coronary heart disease (CHD), further investigation is still needed. The objective of this study was to develop a data mining system using ...

Article

Authors' reply

Constantinou-Deltas, Constantinos D.; Voskarides, Konstantinos (2010)

Article

A combined LS-SVM & MLR QSAR workflow for predicting the inhibition of CXCR3 receptor by quinazolinone analogs

Afantitis, Antreas; Melagraki, G.; Sarimveis, H.; Koutentis, Panayiotis Andreas; Igglessi-Markopoulou, O.; Kollias, G. (2010)

AnovelQSARworkflowis constructed that combines MLR with LS-SVM classification techniques for the identification of quinazolinone analogs as "active" or "nonactive" CXCR3 antagonists. The accuracy of the LS-SVM classification ...

Article

Comparative evaluation of despeckle filtering in ultrasound imaging of the carotid artery

Loizou, Christos P.; Pattichis, Constantinos S.; Christodoulou, Christodoulos I.; Istepanian, Robert Sh Habib; Pantzaris, Marios C.; Nicolaïdes, Andrew N. (2005)

It is well-known that speckle is a multiplicative noise that degrades the visual evaluation in ultrasound imaging. The recent advancements in ultrasound instrumentation and portable ultrasound devices necessitate the need ...

Article

Comparing Different Classifiers for Automatic Age Estimation

Lanitis, A.; Draganova, C.; Christodoulou, Chris C. (2004)

We describe a quantitative evaluation of the performance of different classifiers in the task of automatic age estimation. In this context, we generate a statistical model of facial appearance, which is subsequently used ...

Article

Computerized texture analysis of carotid plaque ultrasonic images can identify unstable plaques associated with ipsilateral neurological symptoms

Kakkos, Stavros K.; Nicolaïdes, Andrew N.; Kyriacou, Efthyvoulos C.; Daskalopoulou, Stella Styliani; Sabetai, Michael; Pattichis, Constantinos S.; Geroulakos, George; Griffin, Maura B.; Thomas, Dominique (2011)

We estimated the value of objective, computerized texture analysis of ultrasonic images in distinguishing carotid plaques associated with neurological ipsilateral symptoms (amaurosis fugax [AmF

Article

Development of a molecular-beacon-based multi-allelic real-time RT-PCR assay for the detection of human coronavirus causing severe acute respiratory syndrome (SARS-CoV): A general methodology for detecting rapidly mutating viruses

Hadjinicolaou, Andreas V.; Farcas, Gabriella A.; Demetriou, Victoria L.; Mazzulli, T.; Poutanen, Susan M.; Willey, B. M.; Low, D. E.; Butany, Jagdish W.; Asa, S. L.; Kain, K. C.; Kostrikis, Leontios G. (2011)

Emerging infectious diseases have caused a global effort for development of fast and accurate detection techniques. The rapidly mutating nature of viruses presents a major difficulty, highlighting the need for specific ...

Article

Effect of zooming on texture features of ultrasonic images

Kakkos, Stavros K.; Nicolaïdes, Andrew N.; Kyriacou, Efthyvoulos C.; Pattichis, Constantinos S.; Geroulakos, George (2006)

Background: Unstable carotid plaques on subjective, visual, assessment using B-mode ultrasound scanning appear as echolucent and heterogeneous. Although previous studies on computer assisted plaque characterisation have ...

Article

Frailty models for arbitrarily censored and truncated data

Huber-Carol, C.; Vonta, Filia (2004)

In this paper, we propose a frailty model for statistical inference in the case where we are faced with arbitrarily censored and truncated data. Our results extend those of Alioum and Commenges (1996), who developed a ...

Article

Indoor and outdoor in situ high-resolution gamma radiation measurements in urban areas of Cyprus

Svoukis, E.; Tsertos, Haralambos (2007)

In situ, high-resolution, gamma-ray spectrometry of a total number of 70 outdoor and 20 indoor representative measurements were performed in preselected, common locations of the main urban areas of Cyprus. Specific activities ...

Article

Indoor radon (222Rn) concentration measurements in Cyprus using high-sensitivity portable detectors

Anastasiou, Tassos; Tsertos, Haralambos; Christofides, Stelios; Christodoulides, George D. (2003)

Using high-sensitivity radon (222Rn) portable detectors (passive electronic devices of the type RADIM3), the airborne 222Rn concentration in the interior of various Cypriot buildings and dwellings was measured. For each ...

Article

An integrated system for the segmentation of atherosclerotic carotid plaque

Loizou, Christos P.; Pattichis, Constantinos S.; Pantzaris, Marios C.; Nicolaïdes, Andrew N. (2007)

In this paper, we propose and evaluate an integrated system for the segmentation of atherosclerotic plaque in ultrasound imaging of the carotid artery based on normalization, speckle reduction filtering, and four different ...

Article

An integrated system for the segmentation of atherosclerotic carotid plaque ultrasound video

Loizou, Christos P.; Petroudi, Styliani; Pantzaris, Marios C.; Nicolaïdes, Andrew N.; Pattichis, Constantinos S. (2014)

The robust border identification of atherosclerotic carotid plaque, the corresponding degree of stenosis of the common carotid artery (CCA), and also the characteristics of the arterial wall, including plaque size, ...

Article

Juxtaluminal hypoechoic area in ultrasonic images of carotid plaques and hemispheric symptoms

Griffin, Maura B.; Kyriacou, Efthyvoulos C.; Pattichis, Constantinos S.; Bond, Dawn; Kakkos, Stavros K.; Sabetai, Michael; Geroulakos, George; Georgiou, Niki; Doré, C. J.; Nicolaïdes, Andrew N. (2010)

Objectives: The aim was to determine the diagnostic value of a juxtaluminal black (hypoechoic) area without a visible echogenic cap (JBA) in ultrasonic images of internal carotid artery plaques. Methods: Ultrasonic images ...

Article

MeDIP real-time qPCR of maternal peripheral blood reliably identifies trisomy 21

Tsaliki, Evdokia; Papageorgiou, Elisavet A.; Spyrou, Christiana; Koumbaris, George L.; Kypri, Elena; Kyriakou, Skevi; Sotiriou, Chrysovalanto; Touvana, Evi; Keravnou, Anna; Karagrigoriou, Alex; Lamnissou, Klea; Velissariou, Voula; Patsalis, Philippos C. (2012)

Objective: To reevaluate the efficiency of the 12 differentially methylated regions (DMRs) used in the methylated DNA immunoprecipitation (MeDIP) real-time quantitative polymerase chain reaction (real-time qPCR) based ...

Article

Molecular beacon-based real-time PCR detection of primary isolates of salmonella typhimurium and salmonella enteritidis in environmental and clinical samples

Hadjinicolaou, Andreas V.; Demetriou, Victoria L.; Emmanuel, M. A.; Kakoyiannis, C. K.; Kostrikis, Leontios G. (2009)

Background. A fast and simple two-step multiplex real-time PCR assay has been developed to replace the traditional, laborious Salmonella serotyping procedure. Molecular beacons were incorporated into the assay as probes ...

Article

Multiscale entropy-based approach to automated surface EMG classification of neuromuscular disorders

Istenič, R.; Kaplanis, P. A.; Pattichis, Constantinos S.; Zazula, D. (2010)

We introduce a novel method for an automatic classification of subjects to those with or without neuromuscular disorders. This method is based on multiscale entropy of recorded surface electromyograms (sEMGs) and support ...

Article

New miRNA profiles accurately distinguish renal cell carcinomas and upper tract urothelial carcinomas from the normal kidney

Zaravinos, Apostolos; Lambrou, George I.; Mourmouras, Nikos; Katafygiotis, Patroklos; Papagregoriou, Gregory N.; Giannikou, Krinio; Delakas, Dimitrios S.; Constantinou-Deltas, Constantinos D. (2014)

Background: Upper tract urothelial carcinomas (UT-UC) can invade the pelvicalyceal system making differential diagnosis of the various histologically distinct renal cell carcinoma (RCC) subtypes and UT-UC, difficult. Correct ...

Article

A new non-invasive prenatal diagnosis of Down syndrome through epigenetic markers and real-time qPCR

Patsalis, Philippos C.; Tsaliki, Evdokia; Koumbaris, George L.; Karagrigoriou, Alex; Velissariou, Voula; Papageorgiou, Elisavet A. (2012)

Introduction: Non-invasive prenatal diagnosis (NIPD) of Down syndrome is rapidly evolving. Currently, two applications for NIPD of Down syndrome have been developed with potential and have displayed positive results