• Article  

      Caspase-independent pathways of programmed cell death: The unraveling of new targets of cancer therapy? 

      Constantinou, Constantina; Papas, Konstantinos A.; Constantinou, Andreas I. (2009)
      In the past few years, accumulating evidence in the literature supports the existence of pathways of caspase-independent programmed cell death (CI-PCD). These pathways are likely to be acting as 'death backup systems' that ...
    • Article  

      Histone H3 tail clipping regulates gene expression 

      Santos-Rosa, H.; Kirmizis, Antonis; Nelson, C.; Bartke, T.; Saksouk, N.; Cote, J.; Kouzarides, T. (2009)
      Induction of gene expression in yeast and human cells involves changes in the histone modifications associated with promoters. Here we identify a histone H3 endopeptidase activity in Saccharomyces cerevisiae that may ...