Browsing by Subject "tumor perfusion"

Now showing items 1-2 of 2

    • Article  

      The role of mechanical forces in tumor growth and therapy 

      Jain, R. K.; Martin, J. D.; Stylianopoulos, T. (2014)
      Tumors generate physical forces during growth and progression. These physical forces are able to compress blood and lymphatic vessels, reducing perfusion rates and creating hypoxia. When exerted directly on cancer cells, ...
    • Article  

      Targeting Inflammation to Improve Tumor Drug Delivery 

      Gkretsi, V.; Zacharia, L. C.; Stylianopoulos, T. (2017)
      Inefficient delivery of drugs is a main cause of chemotherapy failure in hypoperfused tumors. To enhance perfusion and drug delivery in these tumors, two strategies have been developed: vascular normalization, aiming at ...