Browsing by Author "Iacovides, D."
Now showing items 1-4 of 4
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Article
Direct conversion of mouse embryonic fibroblasts into functional keratinocytes through transient expression of pluripotency-related genes
Iacovides, D.; Rizki, G.; Lapathitis, Georgios; Strati, Katerina (2016)The insufficient ability of specialized cells such as neurons, cardiac myocytes, and epidermal cells to regenerate after tissue damage poses a great challenge to treat devastating injuries and ailments. Recent studies ...
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Article
Model-based tumor growth dynamics and therapy response in a mouse model of de novo carcinogenesis
Loizides, C.; Iacovides, D.; Hadjiandreou, M. M.; Rizki, G.; Achilleos, A.; Strati, K.; Mitsis, Georgios D. (2015)
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Article
Model-based tumor growth dynamics and therapy response in a mouse model of de novo carcinogenesis
Loizides, Constantinos A.; Iacovides, D.; Hadjiandreou, M. M.; Rizki, G.; Achilleos, Achilleas P.; Strati, Katerina; Mitsis, Georgios D. (2015)Tumorigenesis is a complex, multistep process that depends on numerous alterations within the cell and contribution from the surrounding stroma. The ability to model macroscopic tumor evolution with high fidelity may ...
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Article
Shared mechanisms in stemness and carcinogenesis: Lessons from oncogenic viruses
Iacovides, D.; Michael, S.; Achilleos, Charis; Strati, Katerina (2013)A rise in technologies for epigenetic reprogramming of cells to pluripotency, highlights the potential of understanding and manipulating cellular plasticity in unprecedented ways. Increasing evidence points to shared ...