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Gene therapies and their potential application in Type 1 Diabetes
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2021-05-14)
Type 1 diabetes (T1D) is an autoimmune metabolic disorder, that arises due to autoimmune destruction of the β-cells in the islets of Langerhans in the pancreas. As a result, there is insufficient insulin production and ...
Human immune responses upon SARS-CoV-2 infection- inflammation and cytokine storm
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2022-12)
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in December 2019 in the city of Wuhan, China, causing the COVID-19 pandemic of acute respiratory ...
Inhibition of Focal Adhesion Kinase as an anti-metastatic therapy
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2021-05-07)
Focal adhesion kinase (FAK), a non-receptor tyrosine kinase, has a physiological role in cell migration, cell survival, wound healing, and cell cycle progression, via both kinase-dependent and kinase-independent functions. ...
The nexus between circRNA and prostate cancer from the complex interventions to treatment expectation
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2022-05-20)
Circular RNAs (circRNAs) are a kind of RNA that results through a non-regular process known as alternative splicing. Because of their possible regulatory activities during gene expression, circRNAs have lately sparked ...
Modelling Glioblastoma Angiogenesis in Drosophila larvae
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2021-05-27)
Glioblastoma multiforme (GBM) is the most common malignant type of cancer of the Central Nervous System (CNS) and is characterized as highly angiogenic. Poor prognosis combined with short lifespan after diagnosis (⁓18 ...