Browsing 002 Σχολή Θετικών και Εφαρμοσμένων Επιστημών / Faculty of Pure and Applied Sciences by Type "Article"

Now showing items 1-20 of 5424

    • Article  

      1,2,3-Dithiazole chemistry in heterocyclic synthesis 

      Christoforou, Irene C.; Koutentis, Panayiotis Andreas; Michaelidou, Sophia S. (2006)
      The chemistry of various 5H-1,2,3-dithiazoles is investigated with emphasis on assisted ring opening and ring closure reactions leading to new heterocycles. Thus on treatment with catalytic tetraalkylammonium iodide ...
    • Article  

      1,2,3-Dithiazoles – new reversible melanin synthesis inhibitors: a chemical genomics study 

      Charalambous, Anna; Koyioni, Maria G.; Antoniades, Ioanna A.; Pegeioti, Despoina; Eleftheriou, Iro; Michaelidou, Sophia S.; Amelichev, Stanislav A.; Konstantinova, Lidia S.; Rakitin, Oleg A.; Koutentis, Panayiotis Andreas; Skourides, Paris A. (2015)
    • Article  

      1,2,3-Dithiazoles-new reversible melanin synthesis inhibitors: A chemical genomics study 

      Charalambous, Anna; Koyioni, Maria; Antoniades, Ioanna; Pegeioti, Despoina; Eleftheriou, Iro; Michaelidou, Sophia S.; Amelichev, Stanislav A.; Konstantinova, L. S.; Rakitin, O. A.; Koutentis, Panayiotis Andreas; Skourides, Paris A. (2015)
      A chemical genomic screen of an in-house library of small molecule heterocycles was carried out using Xenopus laevis embryos. This led to the identification of N-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-4-methoxyaniline ...
    • Article  

      1,2,6-Thiadiazinones as Novel Narrow Spectrum Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) Inhibitors 

      Asquith, Christopher R. M.; Godoi, Paulo H.; Couñago, Rafael M.; Laitinen, Tuomo; Scott, John W.; Langendorf, Christopher G.; Oakhill, Jonathan S.; Drewry, David H.; Zuercher, William J.; Koutentis, Panayiotis A.; Willson, Timothy M.; Kalogirou, Andreas S. (2018)
      We demonstrate for the first time that 4H-1,2,6-thiadiazin-4-one (TDZ) can function as a chemotype for the design of ATP-competitive kinase inhibitors. Using insights from a co-crystal structure of a 3,5-bis(arylamino)-4 ...
    • Article  

      1,3-diphenylbenzo[e][1,2,4]triazin-7(1H)-one: Selected chemistry at the C-6, C-7 and C-8 positions 

      Koutentis, Panayiotis Andreas; Krassos, H.; Lo Re, D. (2011)
      1,3-Diphenylbenzo[e][1,2,4]triazin-7(1H)-one (6) reacts with tetracyanoethylene (TCNE) or tetracyanoethylene oxide (TCNEO) to give the deep green 2-[1,3-diphenylbenzo[e][1,2,4]triazin-7(1H)-ylidene]propanedinitrile (11) ...
    • Article  

      A 1-D coordination polymer based on a Mn40 octagonal super-structure 

      Manoli, Maria; Inglis, R.; Manos, Manolis J.; Papaefstathìou, Giannis S.; Brechin, E. K.; Tasiopoulos, Anastasios J. (2013)
      A 1-D coordination polymer, constructed using a combination of diols and phenolic oximes, contains a novel [Mn9] sub-unit, a nanosized [Mn40] octagonal super-structure and a [Mn21] repeating unit. © 2013 The Royal Society ...
    • Article  

      1-D coordination polymers consisting of a high-spin Mn17 octahedral unit 

      Moushi, Eleni E.; Stamatatos, Theocharis C.; Nastopoulos, Vassilios; Christou, George; Tasiopoulos, Anastasios J. (2009)
      The reaction of [Mn(O2CMe)2] · 4H2O with pdH2 (1,3-propanediol) or mpdH2 (2-methyl-1,3-propanediol) in the presence of NaN3 in MeCN/py (py = pyridine) results in the formation of two new one-dimensional coordination polymers ...
    • Article  

      The 1.76 Å resolution crystal structure of glycogen phosphorylase b complexed with glucose, and CP320626, a potential antidiabetic drug 

      Oikonomakos, Nikos G.; Zographos, Spyros E.; Skamnaki, Vicky T.; Archontis, Georgios Z. (2002)
      CP320626, a potential antidiabetic drug, inhibits glycogen phosphorylase in synergism with glucose. To elucidate the structural basis of synergistic inhibition, we determined the structure of muscle glycogen phosphorylase ...
    • Article  

      2-(2,3,4,5,6-Pentafluorophenyl)-1H-benzo[d]imidazole, a fluorine-rich building block for the preparation of conjugated polymer donors for organic solar cell applications 

      Neophytou, Marios; Ioannidou, Heraklidia A.; Ioannou, Theodosia A.; Chochos, Christos L.; Economopoulos, Solon P.; Koutentis, Panayiotis Andreas; Itskos, Grigorios; Choulis, Stelios A. (2012)
      We have introduced the pentafluorophenyl substituted benzimidazole as a building block of conjugated polymers for optoelectronic applications. We present the synthesis of a copolymer bearing fluorene as the comonomer. A ...
    • Article  

      2-(Pyridin-2-yl)ethanol as a protecting group for carboxylic acids: Chemical and thermal cleavage, and conversion of poly[2-(pyridin-2-yl)ethyl methacrylate] to poly(methacrylic acid) 

      Elladiou, Marios; Patrickios, Costas S. (2012)
      In this communication, we show that 2-(pyridin-2-yl)ethanol is a good protecting group for methacrylic acid (MAA), which can be selectively removed, after polymerization, either chemically under alkaline conditions or ...
    • Article  

      2-Dimensional rare earth metal-organic frameworks based on a hexanuclear secondary building unit as efficient detectors for vapours of nitroaromatics and volatile organic compounds 

      Panagiotou, Nikos; Moscoso, Francisco García; Lopes-Costa, Tânia; Pedrosa, José María; Tasiopoulos, Anastasios J. (Royal Society of Chemistry, 2022-06-10)
      The synthesis, characterisation and capability to selectively detect vapours of volatile organic compounds (VOCs) and nitroaromatic explosives of a new family of 2-dimensional rare earth (RE) MOFs based on a hexanuclear ...
    • Article  

      2-hydroxybenzophenone-controlled self-assembly of enneanuclear lanthanide(III) hydroxo coordination clusters with an “hourglass”-like topology 

      Mylonas-Margaritis, Ioannis; Kitos, Alexandros A.; Panteli, Chrysanthi C.; Skordi, Katerina; Tasiopoulos, Anastasios J.; Bekiari, Vlasoula; Escuer, Albert; Perlepes, Spyros P. (2017)
      Enneanuclear lanthanide(III) hydroxo coordination clusters with an “hourglass”- or “sandglass”-like topology have been synthesized via 2-hydroxybenzophenone-controlled hydrolysis of the metal ions in ethanol
    • Article  

      2-Layer Model for Photopyroelectric Spectroscopy 

      Christofides, Constantinos; Seas, Antonios (1994)
      This paper presents a one-dimensional theory which describes the dependence of the photopyroelectric induced signal on the optical and thermal properties of a two-layer sample, for example a thin film deposited on a ...
    • Article  

      2-step nilpotent lie groups of higher rank 

      Samiou, E. (2002)
      We construct a family of simply connected 2-step nilpotent Lie groups of higher rank such that every geodesic lies in a flat. These are as Riemannian manifolds irreducible and arise from real representations of compact Lie ...
    • Article  

      2nd combined working group and management committee meeting of urine and kidney proteomics COST action 29-30 March 2009, Nafplio, Greece 

      Vlahou, Antonia; Allmaier, G.; Attwood, T.; Bongcam-Rudloff, E.; Charonis, Aristidis S.; Frokiaer, J.; Mischak, H.; Schanstra, J.; Spasovski, G.; Aasberg, A.; Allory, Y.; Arthur, J.; Attwood, T.; Banks, R.; Baumann, M.; Benigni, A.; Bezerianos, Anastasios; Campistol, J. M.; Candiano, G.; Capasso, G.; Carpentier, S.; Dadlez, M.; Constantinou-Deltas, Constantinos D.; Dijilianov, D.; De Zeeuw, D.; Decramer, S.; Dihazi, H.; Domon, B.; Endlich, N.; d'Alche-Buc, F.; D'Haese, P.; Edelman, A.; Egido, J.; El Nahas, M.; Farinazzo, A.; Fernandez-Llama, P.; Feldt-Rasmussen, B.; Frokiaer, J.; Gansevoort, R.; Garbis, S.; Garin, J.; Ghiggeri, G. M.; Gimenez, I.; Granier, C.; Goumenos, Dimitrios S.; Haylor, J. L.; Hilario, M.; Holthofer, H.; Kalousis, Alexandros; Kaski, S.; Knepper, M.; Korneti, P.; Kossida, Sophia A.; Langham, R.; Loftheim, H.; Lopez-Novoa, J.; Luider, T.; Magni, F.; Malats, N.; Martin, J. L.; Mayrhofer, C.; Monsarrat, B.; Mueller, G.; Nielsen, S.; Norling, M.; O'Connell, S.; Ortiz, A.; Perunicic-Pekovic, G.; Planelles, G.; Polenakovic, M.; Promponas, Vasilis J.; Rasic-Milutinovic, Z.; Rehulka, P.; Peter, K.; Righetti, P. G.; Ronco, P.; Ryan, M.; Sánchez-Carbayo, M.; Schanstra, J.; Semmes, J.; Sheehan, D.; Stenman, U. -H; Stodkilde-Jorgensen, L.; Tasic, V.; Theodorescu, D.; Thongboonkerd, V.; Toncheva, D.; Tsillibari, E.; Tsiotis, Georgios; Unwin, R.; Vanholder, R.; Vassilev, D.; Vickers, M. E.; Verhulst, A.; Vilasi, Annalisa; Vlahakos, D.; Vonk, R.; Wright, P. C.; Yamamoto, Tadashi; Yutaka, Y.; Zielenkiewicz, P. (2009)
      EuroKUP (Urine and Kidney Proteomics
    • Article  

      3,4,5,6,7,8,9-heptachlorophenaleno[1,9-bc]pyrazole 

      Demetriadou, Polina K.; Koutentis, Panayiotis Andreas (2009)
      Treatment of perchloro-7H-cyclopropano[a]acenaphthylene 1 with hydrazine hydrate in DMF at ca. 80 °C gives the new 3,4,5,6,7,8,9-heptachlorophenaleno[1,9-bc]pyrazole 2 in 69% yield. This compound is the first example of a ...
    • Article  

      3,4,5-Triarylisothiazoles via C-C coupling chemistry 

      Christoforou, Irene C.; Koutentis, Panayiotis Andreas (2007)
      The regiocontrolled preparation of triarylisothiazoles is presented. 3-Halo-5-phenylisothiazole-4-carbonitriles, 1 (hal = Cl) and 18 (hal = I), are converted into the corresponding 4-bromo derivatives 5 (3-hal = Cl) and ...
    • Article  

      3,5-bis(4-dodecylthiophen-2-yl)-4H-1,2,6-thiadiazin-4-one 

      Ioannidou, Heraklidia A.; Koutentis, Panayiotis Andreas (2012)
      3,5-Dichloro-4H-1,2,6-thiadiazin-4-one 1 reacts with (4-dodecylthiophen-2-yl)trimethylstannane 4 (2.2 equiv.) and Pd(Ph 3P) 2Cl 2 (5 mol%) in acetonitrile at ca. 82 °C to give 3,5-bis(4-dodecylthiophen-2-yl)-4H-1,2,6-thi ...
    • Article  

      3,5-Bis[5-(thiazol-2-yl)thien-2-yl]-4H-1,2,6-thiadiazin-4-one 

      Kalogirou, Andreas S.; Koutentis, Panayiotis A. (2019)
      Stille coupling of 3,5-bis(5-bromothien-2-yl)-4H-1,2,6-thiadiazin-4-one (10) with 2-(tri-n-butylstannyl)thiazole and Pd(Ph3P)2Cl2 in PhMe, at ca. 110 &deg
    • Article  

      3-amino-6-ethoxy-4-phenyl-1H-pyrrolo[2,3-b]pyridine-2,5-dicarbonitrile 

      Koutentis, Panayiotis Andreas; Michaelidou, Sophia S. (2010)
      (Z)-2-(4-Chloro-5H-1,2,3-dithiazol-5-ylideneamino)-6-ethoxy-4-phenylpyridine- 3,5-dicarbonitrile 1, when treated with either triphenylphosphine (4 equiv.) or polymer bound triphenylphosphine (5 equiv.) in dichloromethane ...