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Now showing items 11-19 of 19
Assessment of the risk factors of coronary heart events based on data mining with decision trees
(2010)
Coronary heart disease (CHD) is one of the major causes of disability in adults as well as one of the main causes of death in the developed countries. Although significant progress has been made in the diagnosis and treatment ...
A computationally fast measure of epistasis for 2 SNPs and a categorical phenotype.
(2010)
Complex diseases may be caused by interactions or combined effects between multiple genetic and environmental factors. One of the main limitations of testing for interaction between genetic loci in large whole genome studies ...
Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis
(2010)
Summary Background Complement is a key component of the innate immune system, and variation in genes that regulate its activation is associated with renal and other disease. We aimed to establish the genetic basis for a ...
Cystic diseases of the kidney molecular biology and genetics
(2010)
Context.-Cystic diseases of the kidney are a very heterogeneous group of renal inherited conditions, with more than 33 genes involved and encompassing Xlinked, autosomal dominant, and autosomal recessive inheritance. ...
Data-centric privacy protocol for intensive care grids
(2010)
Modern e-Health systems require advanced computing and storage capabilities, leading to the adoption of technologies like the grid and giving birth to novel health grid systems. In particular, intensive care medicine uses ...
Gamma radiation measurements and dose rates in commonly used building materials in Cyprus
(2010)
A first comprehensive study is presented on radioactivity concentrations and dose rates in 87 commonly used materials, manufactured or imported in Cyprus, for building purposes. The natural radioactivity of 40K, 232Th, ...
Species specificity of the complement inhibitor compstatin investigated by all-atom molecular dynamics simulations
(2010)
The development of compounds to regulate the activation of the complement system in non-primate species is of profound interest because it can provide models for human diseases. The peptide compstatin inhibits protein C3 ...
Deficiencies in the Fanconi Anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer
(2010)
Patients with the rare genetic disease, Fanconi anemia (FA), are highly susceptible to squamous cell carcinomas arising at multiple anatomic sites including the head and neck region. Human papillomaviruses (HPVs), particularly ...