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A combined LS-SVM & MLR QSAR workflow for predicting the inhibition of CXCR3 receptor by quinazolinone analogs
(2010)
AnovelQSARworkflowis constructed that combines MLR with LS-SVM classification techniques for the identification of quinazolinone analogs as "active" or "nonactive" CXCR3 antagonists. The accuracy of the LS-SVM classification ...
Effects of sodium salts of lyotropic anions on low-temperature, ordered lipid monolayers
(2012)
Electrolytes are known to impart considerable disorder to lipid assemblies, including monolayers at the air-water interface, bilayers, and vesicles. In the present work, we have investigated the disordering effect of sodium ...
Separation of acetylcholinesterase inhibitors using polymeric surfactants in polyelectrolyte multilayer coatings
(2012)
The main objective of this study is the use of polymeric surfactants in polyelectrolyte multilayer (PEM) coatings for the separation of the pharmaceutical substances acetylcholinesterase inhibitors (AChEIs). AChEIs are ...
Is vanadate reduced by thiols under biological conditions? Changing the Redox potential of V(V)/V(IV) by complexation in aqueous solution
(2010)
Although dogma states that vanadate is readily reduced by glutathione, cysteine, and other thiols, there are several examples documenting that vanadium(V)-sulfur complexes can form and be observed. This conundrum has ...
Nickel/lanthanide single-molecule magnets: {Ni3Ln} "stars" with a ligand derived from the metal-promoted reduction of di-2-pyridyl ketone under solvothermal conditions
(2010)
Unusual {NiII3LnIII(μ-OR) 6}3+ complexes with a "star" topology have been prepared with ligands derived from the metal-promoted reduction of di-2-pyridyl ketone under solvothermal conditions
Qualitative and quantitative determination of COPs in cypriot meat samples using HPLC determination of the most effective sample preparation procedure
(2013)
This research work describes the development of a fast high-performance liquid chromatography method for the simultaneous determination of five important cholesterol oxidation products (COPs). The influence of various ...
40LoVe and Samba are involved in Xenopusneural development and functionally distinct from hnRNP AB
(2014)
Heterogeneous nuclear ribonucleoproteins (hnRNPs) comprise a large group of modular RNA-binding proteins classified according to their conserved domains. This modular nature, coupled with a large choice of alternative ...
Single-shot optical sectioning using two-color probes in HiLo fluorescence microscopy
(2011)
We describe a wide-field fluorescence microscope setup which combines HiLo microscopy technique with the use of a two-color fluorescent probe. It allows one-shot fluorescence optical sectioning of thick biological moving ...
Comparing intracellular stability and targeting of sulfobetaine quantum dots with other surface chemistries in live cells
(2012)
The in vivo labeling of intracellular components with quantum dots (QDs) is very limited because of QD aggregation in the cell cytoplasm and/or QD confinement into lysosomal compartments. In order to improve intracellular ...
High-resolution whole-mount in situ hybridization using quantum dot nanocrystals
(2012)
The photostability and narrow emission spectra of nanometer-scale semiconductor crystallites (QDs) make them desirable candidates for whole-mount fluorescent in situ hybridization to detect mRNA transcripts in morphologically ...