Browsing Τμήμα Φυσικής / Department of Physics by Subject "Kinetics"
Now showing items 1-8 of 8
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Article
Biological charge transfer via flickering resonance
(2014)Biological electron-transfer (ET) reactions are typically described in the framework of coherent two-state electron tunneling or multistep hopping. However, these ET reactions may involve multiple redox cofactors in van ...
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Article
Glucose-based spiro-isoxazolines: A new family of potent glycogen phosphorylase inhibitors
(2009)A series of glucopyranosylidene-spiro-isoxazolines was prepared through regio- and stereoselective [3+2]-cycloaddition between the methylene acetylated exo-glucal and aromatic nitrile oxides. The deprotected cycloadducts ...
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Article
Glycogen phosphorylase inhibitors: A free energy perturbation analysis of glucopyranose spirohydantoin analogues
(2005)GP catalyzes the phosphorylation of glycogen to Glc-1-P. Because of its fundamental role in the metabolism of glycogen, GP has been the target for a systematic structure-assisted design of inhibitory compounds, which could ...
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Article
Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase
(2005)Glycogen phosphorylase (GP) is currently exploited as a target for inhibition of hepatic glycogenolysis under high glucose conditions. Spirohydantoin of glucopyranose and N-acetyl-β-D-glucopyranosylamine have been identified ...
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Article
Kinetics, in silico docking, molecular dynamics, and MM-GBSA binding studies on prototype indirubins, KT5720, and staurosporine as phosphorylase kinase ATP-binding site inhibitors: The role of water molecules examined
(2011)With an aim toward glycogenolysis control in Type 2 diabetes, we have investigated via kinetic experiments and computation the potential of indirubin (IC 50 > 50 μM), indirubin-3'-oxime (IC 50 = 144 nM), KT5720 (K i = 18.4 ...
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Conference Object
New data on the differential cross section of the dp-elastic scattering at 2.5 GeV obtained with HADES detector
(Proceedings of Science (PoS), 2012)New results on the differential cross section in deuteron-proton elastic scattering are obtained at the deuteron kinetic energy of 2.5 GeV with the HADES spectrometer. The angular range of 69°-125° in the center of mass ...
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Conference Object
Study of the pp → npπ+ reaction at 1.25 GeV with HADES
(CERN, 2010)In pp collisions at 1.25 GeV kinetic energy, the HADES collaboration aimed at investigating the di-electron production related to Δ (1232) Dalitz decay (Δ+ → pe+e-). In order to constrain the models predicting the cross ...
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Article
Triplet excitation energy dynamics in metal-organic frameworks
(2013)Metal-organic frameworks (MOFs) are appealing candidates for use in energy harvesting and concentrating because of their high chromophore density and structural tunability. The ability to engineer electronic excitation ...