Browsing Τμήμα Βιολογικών Επιστημών / Department of Biological Sciences by Title
Now showing items 1-20 of 677
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1,2,3-Dithiazoles-new reversible melanin synthesis inhibitors: A chemical genomics study
(2015)A chemical genomic screen of an in-house library of small molecule heterocycles was carried out using Xenopus laevis embryos. This led to the identification of N-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-4-methoxyaniline ...
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Article
2nd combined working group and management committee meeting of urine and kidney proteomics COST action 29-30 March 2009, Nafplio, Greece
(2009)EuroKUP (Urine and Kidney Proteomics
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Article
40LoVe and Samba are involved in Xenopusneural development and functionally distinct from hnRNP AB
(2014)Heterogeneous nuclear ribonucleoproteins (hnRNPs) comprise a large group of modular RNA-binding proteins classified according to their conserved domains. This modular nature, coupled with a large choice of alternative ...
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Article
The A and B fragments of normal type I procollagen have a similar thermal stability to proteinase digestion but are selectively destabilized by structural mutations
(1987)Previous studies demonstrated that the thermal stability of the procollagen triple helix can be assayed by digesting the protein for short periods with high concentrations of trypsin and chymotrypsin. Here we cleaved human ...
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Article
A ligand-independent integrin β1 mechanosensory complex guides spindle orientation
(2016)Control of spindle orientation is a fundamental process for embryonic development, morphogenesis and tissue homeostasis, while defects are associated with tumorigenesis and other diseases. Force sensing is one of the ...
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Article
Acoustic localization of antbirds in a Mexican rainforest using a wireless sensor network
(2010)Acoustic localization is a promising method to passively observe vocal animal species, but remains difficult and time consuming to employ. To reduce the labor intensity and impact of deployment, an acoustic localization ...
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Acoustic monitoring in terrestrial environments using microphone arrays: Applications, technological considerations and prospectus
(2011)1. Animals produce sounds for diverse biological functions such as defending territories, attracting mates, deterring predators, navigation, finding food and maintaining contact with members of their social group. Biologists ...
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Activation of endogenous FAK via expression of its amino terminal domain in xenopus embryos
(2012)Background: The Focal Adhesion Kinase is a well studied tyrosine kinase involved in a wide number of cellular processes including cell adhesion and migration. It has also been shown to play important roles during embryonic ...
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Doctoral Thesis
ADAMTS13 : molecular recognition of Von Willebrand factor
(University of London, 2006)
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Addressing the Functional Determinants of FAK during Ciliogenesis in Multiciliated Cells
(2017)We previously identified focal adhesion kinase (FAK) as an important regulator of ciliogenesis in multiciliated cells. FAK and other focal adhesion (FA) proteins associate with the basal bodies and their striated rootlets ...
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Doctoral Thesis
Addressing the molecular basis of morphogenetic movements during Xenopus gastrulation with the use of quantum dot nanocrystals the role of Focal Adhesion Kinase (FAK) during Xenopus development
(University of Cyprus, 2011)
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Advances and unmet needs in genetic, basic and clinical science in Alport syndrome: Report from the 2015 International Workshop on Alport Syndrome
(2017)Alport syndrome (AS) is a genetic disease characterized by haematuric glomerulopathy variably associated with hearing loss and anterior lenticonus. It is caused by mutations in the COL4A3, COL4A4 or COL4A5 genes encoding ...
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The Aegean archipelago: A natural laboratory of evolution, ecology and civilisations
(2017)The Aegean archipelago, comprising numerous islands and islets with great heterogeneity in topographic, geological, historical and environmental properties, offers an ideal natural laboratory for ecological and evolutionary ...
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Article
An all-inclusive approach: A universal protocol for the successful amplification of four genetic loci of all Onscidea
(Elsevier, 2022-06-21)Accounting more than 3,700 described species, Oniscidea is the largest and at the same time the only terrestrial isopod suborder inhabiting almost all terrestrial biomes. Despite the great effort dedicated on describing ...
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Alport syndrome from bench to bedside: The potential of current treatment beyond RAAS blockade and the horizon of future therapies
(2014)The hereditary type IV collagen disease Alport syndrome (AS) always leads to end-stage renal failure. Yesterday, for the past 90 years, this course was described as 'inevitable'. Today, RAAS blockade has changed the ...
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Article
Altered metabolic pathways in clear cell renal cell carcinoma: A meta-analysis and validation study focused on the deregulated genes and their associated networks
(2014)Clear cell renal cell carcinoma (ccRCC) is the predominant subtype of renal cell carcinoma (RCC). It is one of the most therapy-resistant carcinomas, responding very poorly or not at all to radiotherapy, hormonal therapy ...
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Altered Phosphorylation, Biosynthesis and Degradation of the 170 kDa Isoform of Topoisomerase II in Amsacrine-Resistant Human Leukemia Cells
(1993)Resistance to amsacrine in HL-60/AMSA is 50-100 fold compared to the parental HL-60/S cells. Synthesis and phosphorylation of topoisomerase II (TOPO II) were 2-3 fold lower in HL-60/AMSA compared to HL-60/S cells metabolically ...
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Article
Altitudinal effect on species richness of Oniscidea (Crustacea
(1992)Species richness decreases with altitude, and at the same rate on all three mountains. The faunal similarity among altitudinal zones is inversely related to species density (total number of species present at each mountain), ...
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Altitudinal terrestrial isopod diversity
(2005)We have assessed the diversity of terrestrial isopods across an elevational and habitat gradient on Mt. Panachaiko (NW Peloponnisos, Greece). Previous knowledge on the biodiversity of this mountain was restricted to very ...