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Paraneoplastic Arthritides: Insights to Pathogenesis, Diagnostic Approach, and Treatment
(2019)
Paraneoplastic arthritides are a group of inflammatory rheumatic syndromes induced by an occult and manifest malignancy, characterized by a wide range of musculoskeletal signs and symptoms that masquerade other rheumatic ...
Successful Ifosfamide Rechallenge in Soft-Tissue Sarcoma
(2015)
OBJECTIVES
Clinical presentation of desmoid tumors
(Springer, 2012)
Desmoid tumors (DT) constitute a rare fibroblastic proliferative disease. They present sporadically or as a manifestation of a hereditary syndrome such as Familial Adenomatous Polyposis (FAP). Despite the absence of ...
Radiogenomics for Precision Medicine With a Big Data Analytics Perspective
(2019)
Precision medicine promises better healthcare delivery by improving clinical practice. Using evidence-based substratification of patients, the objective is to achieve better prognosis, diagnosis, and treatment that will ...
Gemcitabine Re-challenge in Metastatic Soft Tissue Sarcomas: A Therapeutic Option for Selected Patients
(2019)
BACKGROUND/AIM: Treatment options for patients with metastatic soft tissue sarcomas are limited. Re-challenge with a previously successful gemcitabine-based regimen is common. There are no published data to support this ...
Clinical activity and tolerability of a 14-day infusional ifosfamide schedule in soft-tissue sarcoma
(2013)
Background. Soft-tissue sarcomas (STS) are a heterogeneous group of diseases with lack of effective treatments in most cases. Previous data suggest that continuous infusional ifosfamide regimens might improve cytotoxicity ...
The evolution of systemic therapy in sarcoma
(2013)
Approximately 50% of patients with localized soft tissue sarcomas will develop recurrent disease after complete surgical resection, requiring alternative means of treatment. Conventional chemotherapy comprising of doxorubicin ...
Comprehensive surgical treatment as the mainstay of management in retroperitoneal sarcomas: Retrospective study from two non-sarcoma specialist centers
(2017)
Background/Aim: Complete resection, surgical expertise and individualization of patient management in comprehensive oncology centres result in better clinical outcomes in patients presenting with retroperitoneal sarcomas. ...