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dc.contributor.authorConstantopoulos, S. H.en
dc.contributor.authorMalamou-Mitsi, Vassiliki D.en
dc.contributor.authorGoudevenos, J. A.en
dc.contributor.authorPapathanasiou, M. P.en
dc.contributor.authorPavlidis, Nicholasen
dc.contributor.authorPapadimitriou, C.en
dc.creatorConstantopoulos, S. H.en
dc.creatorMalamou-Mitsi, Vassiliki D.en
dc.creatorGoudevenos, J. A.en
dc.creatorPapathanasiou, M. P.en
dc.creatorPavlidis, Nicholasen
dc.creatorPapadimitriou, C.en
dc.date.accessioned2018-06-22T09:52:50Z
dc.date.available2018-06-22T09:52:50Z
dc.date.issued1987
dc.identifier.urihttps://gnosis.library.ucy.ac.cy/handle/7/41535
dc.description.abstractBetween 1981 and 1985 seven patients from three villages of the Metsovo area in Northwestern Greece (population 5000) developed malignant pleural mesothelioma (MPM). The diagnosis was made with pleural biopsy and pleural fluid cytology. Six of these patients have died 18-24 months after the first symptoms (usually dyspnea on exertion) and 1 is still alive after 24 months. Seven MPMs in 5, 000 in five years is about 280 times the expected incidence of 1/1, 000, 000/year. In the same area, endemic pleural calcifications linked to nonoccupational asbestos exposure have recently been reported, but none of our patients with MPM had pleural calcifications. The combination of MPM and pleural plaques in such a high frequency in the same area strongly suggests asbestos fiber as a common etiologic agent. On the other hand, the fact that the combination of MPM and pleural plaques did not occur in the same individuals, suggests a different response to this common offending agent. © 1987 S. Karger AG, Basel.en
dc.language.isoengen
dc.sourceRespirationen
dc.subjectAdulten
dc.subjectFemaleen
dc.subjectMaleen
dc.subjectHumanen
dc.subjectHumansen
dc.subjectMiddle ageden
dc.subjectPriority journalen
dc.subjectClinical articleen
dc.subjectIncidenceen
dc.subjectEpidemiologyen
dc.subjectAsbestosen
dc.subjectGeographic distributionen
dc.subjectGreeceen
dc.subjectMalignant pleural mesotheliomaen
dc.subjectMesotheliomaen
dc.subjectNon-occupational asbestos exposureen
dc.subjectPleuraen
dc.subjectPleura mesotheliomaen
dc.subjectPleura thickeningen
dc.subjectPleural biopsyen
dc.subjectPleural calcificationsen
dc.subjectPleural neoplasmsen
dc.subjectRespiratory systemen
dc.subjectSoil pollutantsen
dc.subjectSpace-time clusteringen
dc.titleHigh incidence of malignant pleural mesothelioma in neighbouring villages of Northwestern Greeceen
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1159/000195212
dc.description.volume51
dc.description.issue4
dc.description.startingpage266
dc.description.endingpage271
dc.author.facultyΙατρική Σχολή / Medical School
dc.author.departmentΙατρική Σχολή / Medical School
dc.type.uhtypeArticleen
dc.contributor.orcidPavlidis, Nicholas [0000-0002-2195-9961]
dc.gnosis.orcid0000-0002-2195-9961


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