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dc.contributor.authorEconomopoulos, T.en
dc.contributor.authorPapageorgiou, S.en
dc.contributor.authorRontogianni, D.en
dc.contributor.authorKaloutsi, V.en
dc.contributor.authorFountzilas, Georgeen
dc.contributor.authorTsatalas, C.en
dc.contributor.authorPavlidis, Nicholasen
dc.contributor.authorPectasides, Dimitriosen
dc.contributor.authorPapageorgiou, E.en
dc.contributor.authorDimopoulos, M. A.en
dc.creatorEconomopoulos, T.en
dc.creatorPapageorgiou, S.en
dc.creatorRontogianni, D.en
dc.creatorKaloutsi, V.en
dc.creatorFountzilas, Georgeen
dc.creatorTsatalas, C.en
dc.creatorPavlidis, Nicholasen
dc.creatorPectasides, Dimitriosen
dc.creatorPapageorgiou, E.en
dc.creatorDimopoulos, M. A.en
dc.date.accessioned2018-06-22T09:52:59Z
dc.date.available2018-06-22T09:52:59Z
dc.date.issued2005
dc.identifier.urihttps://gnosis.library.ucy.ac.cy/handle/7/41598
dc.description.abstractThe purpose of this retrospective study was to illustrate the clinicopathological features of patients presenting with multifocal extranodal non-Hodgkin lymphoma (NHL). Among 810 patients with NHL, 37 cases (4.2%) were found to have multiple extranodal involvement (two or more sites). There were 24 men and 13 women, with a median age of 63 years. The majority of these cases (n = 26) had gastric or intestinal (GI) involvement with or without other extranodal sites. Lung along with another extranodal site was relatively common in the present series. Stratification of the 37 cases according to the International Prognostic Index (IPI) showed that 89% of the patients belonged to the high-risk groups. Diffuse large-B -cell lymphoma (DLBCL) accounted for 62%, and mucosa-associated lymphoma tissue (MALT) lymphoma accounted for 27% of all cases. After induction treatment with anthracycline-based regimens, complete remission was achieved in 21 patients (57%), partial remission was achieved in six patients (16%), and seven patients (19%) had no response, while three patients (8%) were nonevaluable. In conclusion, multifocal extranodal NHL is a heterogeneous group of diseases. The majority of them arise at various sites in the GI tract. DLBCL was the most frequent histological subtype followed by MALT lymphoma. Risk group, as defined by the IPI, was predictive of survival. ©AlphaMed Press.en
dc.language.isoengen
dc.sourceOncologisten
dc.subjectGreeceen
dc.subjectArticleen
dc.subjectCyclophosphamideen
dc.subjectDoxorubicinen
dc.subjectHumanen
dc.subjectPrednisoneen
dc.subject80 and overen
dc.subjectAgeden
dc.subjectHumansen
dc.subjectAdulten
dc.subjectAgeden
dc.subjectFemaleen
dc.subjectMiddle ageden
dc.subjectCancer combination chemotherapyen
dc.subjectPriority journalen
dc.subjectPrognosisen
dc.subjectRetrospective studiesen
dc.subjectRetrospective studyen
dc.subjectClinical articleen
dc.subjectHuman tissueen
dc.subjectSurvival rateen
dc.subjectB cell lymphomaen
dc.subjectMitoxantroneen
dc.subjectNonhodgkin lymphomaen
dc.subjectEpirubicinen
dc.subjectMaleen
dc.subjectClinical featureen
dc.subjectLymphomaen
dc.subjectHigh risk populationen
dc.subjectPathologyen
dc.subjectCancer regressionen
dc.subjectCancer classificationen
dc.subjectHistologyen
dc.subjectRituximaben
dc.subjectNon-hodgkinen
dc.subjectAnthracycline antibiotic agenten
dc.subjectExtranodalen
dc.subjectFludarabine phosphateen
dc.subjectIntestine lymphomaen
dc.subjectMucosa associated lymphoid tissue lymphomaen
dc.subjectMultifocalen
dc.subjectMultifocal extranodal nonhodgkin lymphomaen
dc.subjectMultiple canceren
dc.subjectStomach lymphomaen
dc.subjectVincristine sulfateen
dc.titleMultifocal extranodal non-Hodgkin lymphoma: A clinicopathologic study of 37 cases in Greece, a Hellenic Cooperative Oncology Group Studyen
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1634/theoncologist.10-9-734
dc.description.volume10
dc.description.issue9
dc.description.startingpage734
dc.description.endingpage738
dc.author.facultyΙατρική Σχολή / Medical School
dc.author.departmentΙατρική Σχολή / Medical School
dc.type.uhtypeArticleen
dc.contributor.orcidPavlidis, Nicholas [0000-0002-2195-9961]
dc.gnosis.orcid0000-0002-2195-9961


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