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dc.contributor.authorTheodosopoulos, Theodosiosen
dc.contributor.authorPsychogiou, Vassilikien
dc.contributor.authorYiallourou, Anneza I.en
dc.contributor.authorPolymeneas, Georgeen
dc.contributor.authorKondi-Pafiti, Agathien
dc.contributor.authorPapaconstantinou, Ioannisen
dc.contributor.authorVoros, Dionysiosen
dc.creatorTheodosopoulos, Theodosiosen
dc.creatorPsychogiou, Vassilikien
dc.creatorYiallourou, Anneza I.en
dc.creatorPolymeneas, Georgeen
dc.creatorKondi-Pafiti, Agathien
dc.creatorPapaconstantinou, Ioannisen
dc.creatorVoros, Dionysiosen
dc.date.accessioned2018-06-22T09:53:16Z
dc.date.available2018-06-22T09:53:16Z
dc.date.issued2012
dc.identifier.urihttps://gnosis.library.ucy.ac.cy/handle/7/41747
dc.description.abstractPurpose: Retroperitoneal sarcomas (RPs) are characterized by slow indolent growth and metastasize at a late point in their natural course. The purpose of this study was to review our experience in the management of RSs and identify prognostic factors for local control and survival. Methods: Between January 1990 and December 2010, the hospital records of 75 patients with RSs were retrospectively studied. Sixty-four (85.3%) patients had undergone surgical resection in our hospital for primary RS, whereas 11 (14.7%) were referred to our department for recurrent disease. Results: The patient median age was 57 years. Median tumor size was 18.5 cm. The most common histologic type was liposarcoma (44%) followed by leiomyosarcoma (17%), paraganglioma (10%), malignant fibrous histiocytoma (6.5%) and rare tumors such as 2 chondrosarcomas and 1 pecoma. Complete initial resection with negative macroscopic margins (RO) was achieved in 39 (60.9%) patients. En bloc resection of adjacent organs was required in 8 (12.5%) patients with primary RS and in 8 (72.9%) with recurrent disease. Mortality rate was 4%. For the group of patients initially treated in our hospital, 1-year recurrence rate was 34.3%. The 3- and 5-year overall survival rates were 56.2% and 53.1%, respectively. Satellite tumors were recognised in 13 (20.3%) patients treated for primary RS, from whom 11 (84%) recurred within oneyear. Seven patients received adjuvant chemotherapy. Conclusion: Radical surgical resection is the treatment of choice for patients with primary and locally recurrent RSs. © 2012 Zerbinis Medical Publications.en
dc.language.isoengen
dc.sourceJournal of B.U.ON.en
dc.subjectSarcomaen
dc.subjectLiposarcomaen
dc.subjectMesenchymal tissueen
dc.subjectRetroperitoneumen
dc.subjectSatellite tumorsen
dc.subjectSoft tissueen
dc.titleManagement of retroperitoneal sarcomas: Main prognostic factors for local recurrence and survivalen
dc.typeinfo:eu-repo/semantics/article
dc.description.volume17
dc.description.issue1
dc.description.startingpage138
dc.description.endingpage142
dc.author.facultyΙατρική Σχολή / Medical School
dc.type.uhtypeArticleen
dc.contributor.orcidYiallourou, Anneza I. [0000-0003-1237-1661]
dc.contributor.orcidPapaconstantinou, Ioannis [0000-0002-4614-9041]
dc.gnosis.orcid0000-0003-1237-1661
dc.gnosis.orcid0000-0002-4614-9041


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