Clinicopathological features and management of hepatic vascular tumors. A 20-year experience in a Greek University Hospital

Abstract

Purpose: The aim of this study was to review the clini cal features, diagnostic modalities, treatment options anc pathological characteristics of various types of hepatic vascular tumors treated in our Institution over the last 2( years. Methods: From 1991 to 2011, 761 cases of various hepatic lesions, benign and malignant, were surgically treated ir our hospital. Among these, 56 (7.35%) hepatectomy specimens referred to vascular tumors. The records of these patients were retrieved and demographics , tumor characteristics, treatment, and actuarial survival were analyzed The various therapeutic procedures, postoperative compli cations, follow-up data and the pre-and postoperative diagnostic difficulties were registered and analyzed. Results: Pathological examination showed: hepatic hemangiomas in 35 (62.5%) patients (80% females), hepatic angiosarcomas in 7 patients (12.5%; males 71.4%), hepatic epithelioid hemangioendotheliomas in 9 16% females 50%) and hepatic angiomyolipomas in 5 patients (9%; females 60%). Conclusions: Vascular tumors of the liver comprise a heterogeneous group of neoplasms, benign, malignant and of intermediate degree of malignant behavior. These lesions can create great diagnostic difficulties, pre- and postoperative considerations, but the correct pathological diagnosis and classification of vascular hepatic tumors are most of the times mandatory in order to choose the proper theraveutic actions.