dc.contributor.author | Kessler, Ulf | en |
dc.contributor.author | Mungnirandr, A. | en |
dc.contributor.author | Nelle, M. | en |
dc.contributor.author | Nimmo, A. F. | en |
dc.contributor.author | Zachariou, Zacharias | en |
dc.contributor.author | Berger, Steffen | en |
dc.creator | Kessler, Ulf | en |
dc.creator | Mungnirandr, A. | en |
dc.creator | Nelle, M. | en |
dc.creator | Nimmo, A. F. | en |
dc.creator | Zachariou, Zacharias | en |
dc.creator | Berger, Steffen | en |
dc.date.accessioned | 2018-06-22T09:53:46Z | |
dc.date.available | 2018-06-22T09:53:46Z | |
dc.date.issued | 2006 | |
dc.identifier.uri | https://gnosis.library.ucy.ac.cy/handle/7/42015 | |
dc.description.abstract | Objective: To assess the relationship between early laboratory parameters, disease severity, type of management (surgical or conservative) and outcome in necrotizing enterocolitis (NEC). Study design: Retrospective collection and analysis of data from infants treated in a single tertiary care center (1980 to 2002). Data were collected on disease severity (Bell stage), birth weight (BW), gestational age (GA) and pre-intervention laboratory parameters (leukocyte and platelet counts, hemoglobin, lactate, C-reactive protein). Results: Data from 128 infants were sufficient for analysis. Factors significantly associated with survival were Bell stage (P<0.05), lactate (P<0.05), BW and GA (P<0.01, P<0.001, respectively). From receiver operating characteristics curves, the highest predictive value resulted from a score with 0 to 8 points combining BW, Bell stage, lactate and platelet count (P<0.001). At a cutoff level of 4.5 sensitivity and specificity for predicting survival were 0.71 and 0.72, respectively. Conclusion: Some single parameters were associated with poor outcome in NEC. Optimal risk stratification was achieved by combining several parameters in a score. | en |
dc.language.iso | eng | en |
dc.source | Journal of Perinatology | en |
dc.title | A simple presurgical necrotizing enterocolitis-mortality scoring system | en |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | 10.1038/sj.jp.7211613 | |
dc.description.volume | 26 | |
dc.description.issue | 12 | |
dc.description.startingpage | 764 | |
dc.description.endingpage | 768 | |
dc.author.faculty | Ιατρική Σχολή / Medical School | |
dc.author.department | Ιατρική Σχολή / Medical School | |
dc.type.uhtype | Article | en |
dc.contributor.orcid | Zachariou, Zacharias [0000-0001-8305-8037] | |
dc.contributor.orcid | Kessler, Ulf [0000-0002-9547-9426] | |
dc.gnosis.orcid | 0000-0001-8305-8037 | |
dc.gnosis.orcid | 0000-0002-9547-9426 | |