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In vitro antioxidant activity and phenolic content of Cedrus brevifolia bark

dc.contributor.authorCretu, E.en
dc.contributor.authorSalminen, J. -Pen
dc.contributor.authorKaronen, M.en
dc.contributor.authorMiron, A.en
dc.contributor.authorCharalambous, Christinaen
dc.contributor.authorConstantinou, Andreas I.en
dc.contributor.authorAprotosoaie, A. C.en
dc.creatorCretu, E.en
dc.creatorSalminen, J. -Pen
dc.creatorKaronen, M.en
dc.creatorMiron, A.en
dc.creatorCharalambous, Christinaen
dc.creatorConstantinou, Andreas I.en
dc.creatorAprotosoaie, A. C.en
dc.date.accessioned2019-11-04T12:50:29Z
dc.date.available2019-11-04T12:50:29Z
dc.date.issued2014
dc.identifier.issn1934-578X
dc.identifier.urihttp://gnosis.library.ucy.ac.cy/handle/7/53039
dc.description.abstractA raw extract and four extractive fractions were obtained from Cedrus brevifolia (Cyprus cedar) bark. They were all studied regarding the phenolic content and profile using spectrophotometry and HPLC-DAD-ESI-MS. The antioxidant activity was investigated using in vitro assays: DPPH and ABTS radicals scavenging and reducing power assays. The ethyl acetate fraction had the highest total phenolic and proanthocyanidin contentsen
dc.description.abstracta taxifolin-O-hexoside, catechin, epicatechin and procyanidin oligomers (three dimers, two trimers) were identified in this fraction. The ethyl acetate fraction was found to possess the highest DPPH and ABTS radicals scavenging effects (EC50=13.9 ± 0.3 and 2.3 ± 0.0 μg/mL, respectively) and reducing capacity (EC50=9.1 ± 0.1 μg/mL). Antioxidant effects were highly correlated with total phenolic and proanthocyanidin contents (r=0.89-0.99). These results suggest that Cedrus brevifolia bark is a new source of antioxidants.en
dc.sourceNatural Product Communicationsen
dc.source.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84898782365&partnerID=40&md5=caf52d59bf1839c23d9c4afb7c5700b5
dc.subjectarticleen
dc.subjectcontrolled studyen
dc.subjectnonhumanen
dc.subjectcomparative studyen
dc.subjectin vitro studyen
dc.subjectAntioxidantsen
dc.subjectPhenolsen
dc.subjectphenol derivativeen
dc.subjectChromatography, High Pressure Liquiden
dc.subject1,1 diphenyl 2 picrylhydrazylen
dc.subjectantioxidant activityen
dc.subjectFree Radical Scavengersen
dc.subjectgallic aciden
dc.subjectPicratesen
dc.subjectPlant Extractsen
dc.subjectcatechinen
dc.subjectbarken
dc.subjectPlant Barken
dc.subjectProanthocyanidinsen
dc.subjectprocyanidinen
dc.subjectTaxifolinen
dc.subjectABTSen
dc.subjectABTS radical scavenging assayen
dc.subjectacetic acid ethyl esteren
dc.subjectBenzothiazolesen
dc.subjectBiphenyl Compoundsen
dc.subjectCedrusen
dc.subjectCedrus brevifoliaen
dc.subjectDPPHen
dc.subjectepicatechinen
dc.subjectFree radical scavengingen
dc.subjectHPLC-DAD-ESI-MSen
dc.subjectoxidation reduction potentialen
dc.subjectproanthocyanidinen
dc.subjectProcyanidinsen
dc.subjectReducing poweren
dc.subjectSpectrometry, Mass, Electrospray Ionizationen
dc.subjectSulfonic Acidsen
dc.titleIn vitro antioxidant activity and phenolic content of Cedrus brevifolia barken
dc.typeinfo:eu-repo/semantics/article
dc.description.volume9
dc.description.startingpage481
dc.description.endingpage482
dc.author.facultyΣχολή Θετικών και Εφαρμοσμένων Επιστημών / Faculty of Pure and Applied Sciences
dc.author.departmentΤμήμα Βιολογικών Επιστημών / Department of Biological Sciences
dc.type.uhtypeArticleen
dc.description.notes<p>Cited By :2</p>en
dc.source.abbreviationNat.Pro.Comm.en
dc.contributor.orcidConstantinou, Andreas I. [0000-0003-0365-1821]
dc.gnosis.orcid0000-0003-0365-1821


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