Use of coreceptors other than CCR5 by non-syncytium-inducing adult and pediatric isolates of human immunodeficiency virus type 1 is rare in vitro
dc.contributor.author | Zhang, Y. -J | en |
dc.contributor.author | Dragic, T. | en |
dc.contributor.author | Cao, Yun Zhen | en |
dc.contributor.author | Kostrikis, Leontios G. | en |
dc.contributor.author | Kwon, D. S. | en |
dc.contributor.author | Littman, D. R. | en |
dc.contributor.author | Kewalramani, V. N. | en |
dc.contributor.author | Moore, J. P. | en |
dc.creator | Zhang, Y. -J | en |
dc.creator | Dragic, T. | en |
dc.creator | Cao, Yun Zhen | en |
dc.creator | Kostrikis, Leontios G. | en |
dc.creator | Kwon, D. S. | en |
dc.creator | Littman, D. R. | en |
dc.creator | Kewalramani, V. N. | en |
dc.creator | Moore, J. P. | en |
dc.date.accessioned | 2019-11-04T12:52:55Z | |
dc.date.available | 2019-11-04T12:52:55Z | |
dc.date.issued | 1998 | |
dc.identifier.issn | 0022-538X | |
dc.identifier.uri | http://gnosis.library.ucy.ac.cy/handle/7/53464 | |
dc.description.abstract | We have tested a panel of pediatric and adult human immunodeficiency virus type 1 (HIV-1) primary isolates for the ability to employ the following proteins as coreceptors during viral entry: CCR1, CCR2b, CCR3, CCR4, CCR5, CCR8, CXCR4, Bonzo, BOB, GPR1, V28, US28, and APJ. Most non-syncytium- inducing isolates could utilize only CCR5. All syncytium-inducing viruses used CXCR4, some also employed V28, and one (DH123) used CCR8 and APJ as well. A longitudinal series of HIV-1 subtype B isolates from an infected infant and its mother utilized Bonzo efficiently, as well as CCR5. The maternal isolates, which were syncytium inducing, also used CXCR4, CCRS, V28, and APJ. | en |
dc.source | Journal of virology | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031710044&partnerID=40&md5=101021946b1c32b917111fd2be14e73b | |
dc.subject | article | en |
dc.subject | Adult | en |
dc.subject | Female | en |
dc.subject | Male | en |
dc.subject | human | en |
dc.subject | Humans | en |
dc.subject | controlled study | en |
dc.subject | priority journal | en |
dc.subject | Pregnancy | en |
dc.subject | HIV Infections | en |
dc.subject | nonhuman | en |
dc.subject | human cell | en |
dc.subject | CD4-Positive T-Lymphocytes | en |
dc.subject | Infant | en |
dc.subject | HIV-1 | en |
dc.subject | Cell Line | en |
dc.subject | Receptors, CCR5 | en |
dc.subject | Transfection | en |
dc.subject | virus isolation | en |
dc.subject | Genes, env | en |
dc.subject | strain difference | en |
dc.subject | Disease Transmission, Vertical | en |
dc.subject | human immunodeficiency virus 1 | en |
dc.subject | virus cell interaction | en |
dc.subject | Receptors, CXCR4 | en |
dc.subject | Genetic Complementation Test | en |
dc.subject | membrane fusion | en |
dc.subject | Receptors, HIV | en |
dc.subject | syncytium | en |
dc.subject | virus receptor | en |
dc.subject | Virus Replication | en |
dc.title | Use of coreceptors other than CCR5 by non-syncytium-inducing adult and pediatric isolates of human immunodeficiency virus type 1 is rare in vitro | en |
dc.type | info:eu-repo/semantics/article | |
dc.description.volume | 72 | |
dc.description.startingpage | 9337 | |
dc.description.endingpage | 9344 | |
dc.author.faculty | Σχολή Θετικών και Εφαρμοσμένων Επιστημών / Faculty of Pure and Applied Sciences | |
dc.author.department | Τμήμα Βιολογικών Επιστημών / Department of Biological Sciences | |
dc.type.uhtype | Article | en |
dc.description.notes | <p>Cited By :142</p> | en |
dc.source.abbreviation | J.Virol. | en |
dc.contributor.orcid | Kostrikis, Leontios G. [0000-0002-5340-7109] | |
dc.gnosis.orcid | 0000-0002-5340-7109 |
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