Browsing Τμήμα Βιολογικών Επιστημών / Department of Biological Sciences by Submit Date
Now showing items 21-28 of 28
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Master Thesis Open Access
Mechanical Cell Membrane stimulation using Magnetic Tweezers increases cell membrane stiffness through integrin dependent and independent mechanisms
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2022-12)Several cellular processes, such as proliferation, migration tissue morphogenesis and tissue regeneration, are closely regulated by the cells ability to sense their microenvironment and translate mechanical stimuli to ...
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Master Thesis Open Access
Extracellular Regulated Kinase (ERK): A novel regulator in the development and function of cilia
(2023-06-14)The role of cilia in biomedicine is becoming more and more recognized since defects in ciliary structure and function induce ciliopathies such as cystic kidney disease, neurological anomalies, obesity, blindness, and ...
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Master Thesis Open Access
Bacterial Species Antagonizing Pseudomonas aeruginosa Infection
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2021-05-27)Microbial species rarely exist in isolation in nature. Epithelial interfaces, such as the bilaterian intestine or the mammalian lung, harbour polymicrobial communities increasing infection complexity at these sites. We ...
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Master Thesis Open Access
Gene therapies and their potential application in Type 1 Diabetes
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2021-05-14)Type 1 diabetes (T1D) is an autoimmune metabolic disorder, that arises due to autoimmune destruction of the β-cells in the islets of Langerhans in the pancreas. As a result, there is insufficient insulin production and ...
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Master Thesis Open Access
Genetic Characterization of a Novel HIV-1 Circulating Recombinant Form (CRF91_cpx) and Identification of Three Additional Putative CRFs: Increased Prevalence of URFs and CRFs in the Polyphyletic HIV-1 Infection in Cyprus.
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2022-05-27)HIV is characterized by a high degree of genetic variation, as it is evident from numerous genetically distinct subtypes (within the major group M) and circulating recombinant forms (CRFs). The genetic diversity of HIV is ...
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Master Thesis Open Access
Reproductive biology and growth of the alien Red Sea goatfish Parupeneus forsskali (Fourmanoir & Guézé, 1976) off the coast of Cyprus
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2021-12-15)Goatfish (family Mullidae) are of great commercial and economical importance around the world, including in the Mediterranean Sea, where six goatfish species have been recorded. Four of those species are alien to the ...
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Master Thesis Open Access
The genetic basis of Autosomal Dominant Polycystic Kidney Disease (ADPKD) in two Cypriot Families and the development of a robust PKD1 and PKD2 mutation screening test using amplicon-based Next-Generation Sequencing (NGS)
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2021-06-11)Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common hereditary kidney diseases, with a frequency of 1 in 1000 people in the general population. This progressive disorder is mainly caused by ...
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Master Thesis Open Access
Molecular pathways affected by HBx protein and their targeting for therapy of Hepatocellular carcinoma
(2022-12-09)Hepatitis B virus (HBV) infection can cause several types of liver disease including acute hepatitis, chronic hepatitis, and liver cirrhosis. It is also considered a significant risk factor for Hepatocellular carcinoma ...