dc.contributor.author | Zis, Panagiotis | en |
dc.contributor.author | Sarrigiannis, Ptolemaios Georgios | en |
dc.contributor.author | Rao, Dasappaiah Ganesh | en |
dc.contributor.author | Hadjivassiliou, Marios | en |
dc.creator | Zis, Panagiotis | en |
dc.creator | Sarrigiannis, Ptolemaios Georgios | en |
dc.creator | Rao, Dasappaiah Ganesh | en |
dc.creator | Hadjivassiliou, Marios | en |
dc.date.accessioned | 2021-02-23T14:38:39Z | |
dc.date.available | 2021-02-23T14:38:39Z | |
dc.date.issued | 2018 | |
dc.identifier.uri | http://gnosis.library.ucy.ac.cy/handle/7/64204 | |
dc.description.abstract | Background: Gluten neuropathy (GN) is defined as an otherwise idiopathic peripheral neuropathy in the presence of serological evidence of gluten sensitivity (positive native gliadin antibodies and/or transglutaminase or endomysium antibodies). We aimed to compare the quality of life (QoL) of GN patients with that of control subjects and to investigate the effects of a gluten-free diet (GFD) on the QoL. Methods: All consecutive patients with GN attending a specialist neuropathy clinic were invited to participate. The Overall Neuropathy Limitations Scale (ONLS) was used to assess the severity of the neuropathy. The 36-Item Short Form Survey (SF-36) questionnaire was used to measure participants&rsquo | en |
dc.description.abstract | QoL. A strict GFD was defined as effectively being able to eliminate all circulating gluten sensitivity-related antibodies. Results: Fifty-three patients with GN and 53 age- and gender-matched controls were recruited. Compared to controls, GN patients showed significantly worse scores in the physical functioning, role limitations due to physical health, energy/fatigue, and general health subdomains of the SF-36. After adjusting for age, gender, and disease severity, being on a strict GFD correlated with better SF-36 scores in the pain domain of the SF-36 (beta 0.317, p = 0.019) and in the overall health change domain of the SF-36 (beta 0.306, p = 0.017). Conclusion: In GN patients, physical dysfunctioning is the major determinant of poor QoL compared to controls. Routine checking of the elimination of gluten sensitivity-related antibodies that results from a strict GFD should be encouraged, as such elimination ameliorates the overall pain and health scores, indicating a better QoL. | en |
dc.language.iso | en | en |
dc.source | Nutrients | en |
dc.source.uri | https://www.mdpi.com/2072-6643/10/6/662 | |
dc.title | Quality of Life in Patients with Gluten Neuropathy: A Case-Controlled Study | en |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | 10.3390/nu10060662 | |
dc.description.volume | 10 | |
dc.description.issue | 6 | |
dc.author.faculty | Ιατρική Σχολή / Medical School | |
dc.author.department | Ιατρική Σχολή / Medical School | |
dc.type.uhtype | Article | en |
dc.contributor.orcid | Zis, Panagiotis [0000-0001-8567-3092] | |
dc.contributor.orcid | Sarrigiannis, Ptolemaios Georgios [0000-0002-8380-8755] | |
dc.contributor.orcid | Hadjivassiliou, Marios [0000-0003-2542-8954] | |
dc.contributor.orcid | Rao, Dasappaiah Ganesh [0000-0002-6350-8536] | |
dc.gnosis.orcid | 0000-0001-8567-3092 | |
dc.gnosis.orcid | 0000-0002-8380-8755 | |
dc.gnosis.orcid | 0000-0003-2542-8954 | |
dc.gnosis.orcid | 0000-0002-6350-8536 | |