Browsing by Subject "gene expression regulation"
Now showing items 21-26 of 26
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Regulation of Lactate Dehydrogenase Gene Expression by AMP‐dependent Protein Kinase Subunits
(1986)
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Selective activation of TNFR1 and NF-ΚB inhibition by a novel biyouyanagin analogue promotes apoptosis in acute leukemia cells
(2016)Background: Acquired resistance towards apoptosis is a hallmark of cancer. Elimination of cells bearing activated oncogenes or stimulation of tumor suppressor mediators may provide a selection pressure to overcome resistance. ...
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Shared mechanisms in stemness and carcinogenesis: Lessons from oncogenic viruses
(2013)A rise in technologies for epigenetic reprogramming of cells to pluripotency, highlights the potential of understanding and manipulating cellular plasticity in unprecedented ways. Increasing evidence points to shared ...
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Article
Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis
(2015)Introduction: Basal-like breast cancer (BLBC) is an aggressive subtype often characterized by distant metastasis, poor patient prognosis, and limited treatment options. Therefore, the discovery of alternative targets to ...
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vavCre transgenic mice: A tool for mutagenesis in hematopoietic and endothelial lineages
(2002)Cre transgenic mice can be used to delete gene sequences flanked by loxP sites in specific somatic tissues. We have generated vavCre transgenic mice, which can be used to inactivate genes specifically in adult hematopoietic ...