Steps toward understanding the inheritance of repressive methyl-lysine marks in histones
Preissner, T. S.
SourceCold Spring Harbor Symposia on Quantitative Biology
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Kirmizis, Antonis; Bartley, S. M.; Kuzmichev, A.; Margueron, R.; Reinberg, D.; Green, R.; Farnham, P. J. (2004)Polycomb group (PcG) complexes 2 and 3 are involved in transcriptional silencing. These complexes contain a histone lysine methyltransferase (HKMT) activity that targets different lysine residues on histones H1 or H3 in ...
Loss of Nat4 and its associated histone H4 N-terminal acetylation mediates calorie restriction-induced longevity Molina-Serrano, D.; Schiza, V.; Demosthenous, Christis; Stavrou, Emmanouil; Oppelt, J.; Kyriakou, DImitris; Liu, W.; Zisser, G.; Bergler, H.; Dang, W.; Kirmizis, Antonis (2016)Changes in histone modifications are an attractive model through which environmental signals, such as diet, could be integrated in the cell for regulating its lifespan. However, evidence linking dietary interventions with ...
Molina-Serrano, D.; Schiza, V.; Kirmizis, Antonis (2013)Epigenetic modifications, including those occurring on DNA and on histone proteins, control gene expression by establishing and maintaining different chromatin states. In recent years, it has become apparent that epigenetic ...