Browsing Τμήμα Βιολογικών Επιστημών / Department of Biological Sciences by Submit Date

Article

HIV-1 subtype distribution and its demographic determinants in newly diagnosed patients in Europe suggest highly compartmentalized epidemics

Abecasis, A. B.; Wensing, A. M. J.; Paraskevis, Dimitrios N.; Vercauteren, J.; Theys, K.; Van de Vijver, D. A. M. C.; Albert, Jan; Åsjö, Birgitta; Balotta, Claudia; Beshkov, Danail; Camacho, Ricardo J.; Clotet, B.; De Gascun, C.; Griskevicius, A.; Grossman, Z.; Hamouda, O.; Horban, A.; Kolupajeva, T.; Korn, K.; Kostrikis, Leontios G.; Kücherer, C.; Liitsola, K.; Linka, M.; Nielsen, C.; Otelea, D.; Paredes, R.; Poljak, M.; Puchhammer-Stöckl, E.; Schmit, J. -C; Sönnerborg, A.; Stanekova, D.; Stanojevic, M.; Struck, D.; Boucher, C. A. B.; Vandamme, A. -M (2013)

Background: Understanding HIV-1 subtype distribution and epidemiology can assist preventive measures and clinical decisions. Sequence variation may affect antiviral drug resistance development, disease progression, ...

Article

Global Dispersal Pattern of HIV Type 1 Subtype CRF01_AE: A Genetic Trace of Human Mobility Related to Heterosexual Sexual Activities Centralized in Southeast Asia

Angelis, Konstantinos; Albert, Jan; Mamais, Ioannis A.; Magiorkinis, Gkikas; Hatzakis, Angelos E.; Hamouda, Osamah; Struck, Daniel; Vercauteren, Jurgen; Wensing, Annemarie M. J.; Alexiev, Ivailo; Åsjö, Birgitta; Balotta, Claudia; Camacho, Ricardo J.; Coughlan, Suzie; Griskevicius, Algirdas; Grossman, Zehava; Horban, Andrzej; Kostrikis, Leontios G.; Lepej, Snjezana; Liitsola, Kirsi; Linka, Marek; Nielsen, Claus; Otelea, Dan; Paredes, Roger; Poljak, Mario; Puchhammer-Stöckl, Elisabeth; Schmit, Jean-Claude; Sönnerborg, Anders; Staneková, Danica; Stanojevic, Maja; Boucher, Charles A. B.; Kaplan, Lauren; Vandamme, Anne-Mieke; Paraskevis, Dimitrios N. (2014)

Article

Cellular HIV type 1 DNA levels are equivalent among drug-sensitive and drug-resistant strains in newly diagnosed and antiretroviral naive patients

Antoniadou, Zoi Anna; Hezka, Johana; Kousiappa, Ioanna; Mamais, Ioannis A.; Skoura, Lemonia G.; Pilalas, Dimitrios; Metallidis, Simeon A.; Nicolaidis, Pavlos; Malisiovas, Nikolaos; Kostrikis, Leontios G. (2014)

The emergence of resistance against current antiretroviral drugs to human immunodeficiency virus type 1 (HIV-1) is an increasingly important concern to the continuous success of antiretroviral therapy to HIV-1-infected ...

Article

Short communication: Molecular epidemiology of HIV type 1 infection in northern Greece (2009-2010): Evidence of a transmission cluster of HIV Type 1 Subtype A1 drug-resistant strains among men who have sex with men

Antoniadou, Zoi Anna; Kousiappa, Ioanna; Skoura, Lemonia G.; Pilalas, Dimitrios; Metallidis, Simeon A.; Nicolaidis, Pavlos; Malisiovas, Nikolaos; Kostrikis, Leontios G. (2014)

A prospective molecular epidemiology study of HIV-1 infection was conducted in newly diagnosed and antiretroviral-naive patients in Northern Greece between 2009 and 2010 using a predefined enrolling strategy. Phylogenetic ...

Article

Drosophila immune priming against Pseudomonas aeruginosa is short-lasting and depends on cellular and humoral immunity

Apidianakis, Yiorgos; Christofi, T. (2013)

Immune responses are traditionally divided into the innate and the adaptive arm, both of which are present in vertebrates, while only the innate arm is found in invertebrates. Immune priming experiments in Drosophila ...

Article

A holo'ome approach in colon cancer: We change as we age

Apidianakis, Yiorgos; Eliopoulos, Aristides G. (2015)

Book

Biogeography and Biodiversity of the Aegean. In honour of Prof. Moysis Mylonas

Sfenthourakis, Spyros; Pafilis, Panayiotis; Parmakelis, Aristeidis; Poulakakis, Nikos; Triantis, Kostas; Sfenthourakis, Spyros [0000-0003-3213-2502] (Broken Hill Publishers, 2018)

Article

Attenuation of drug-stimulated topoisomerase II-DNA cleavable complex formation in wild-type HL-60 cells treated with an intracellular calcium buffer is correlated with decreased cytotoxicity and site-specific hypophosphorylation of topoisomerase IIα

Aoyama, M.; Grabowski, D. R.; Dubyak, G. R.; Constantinou, Andreas I.; Rybicki, L. A.; Bukowski, R. M.; Ganapathi, M. K.; Hickson, I. D.; Ganapathi, R. (1998)

Topoisomerase II (topo II), an essential enzyme for cell viability, is also the target for clinically important anti-neoplastic agents that stimulate topo II-mediated DNA scission. The role of alterations in topo IIα ...

Book Chapter

Drosophila melanogaster as a versatile model for the discovery of drugs effective against human Microbe-induced infection and pathology

Apidianakis, Yiorgos; Kontoyiannis, D. P. (CABI Publishing, 2012)

Article

Profiling early infection responses: Pseudomonas aeruginosa eludes host defenses by suppressing antimocrobial peptide gene expression

Apidianakis, Yiorgos; Mindrinos, M. N.; Xiao, W.; Lau, G. W.; Baldini, R. L.; Davis, R. W.; Rahme, L. G. (2005)

Insights into the host factors and mechanisms mediating the primary host responses after pathogen presentation remain limited, due in part to the complexity and genetic intractability of host systems. Here, we employ the ...

Article

Cystic fibrosis patients from the black sea region: The 1677delTA mutation

Angelicheva, D.; Boteva, Kalina; Jordanova, A.; Savov, A.; Kufardjieva, A.; Tolun, A.; Telatar, M.; Akarsubaşi, A.; Köprübaşi, F.; Aydoǧdu, S.; Demirkol, M.; Kurdoǧlu, G.; Constantinou-Deltas, Constantinos D.; Georgiou, Christina; Dean, M.; Ivaschenko, T.; Baranov, V.; Kalaydjieva, L. (1994)

A 2 bp deletion in exon 10 of the CFTR gene, 1677delTA, which is very rare among CF chromosomes worldwide, was found to be a relatively common cause of cystic fibrosis in countries located in the region of the Black Sea. ...

Article

40LoVe and Samba are involved in Xenopusneural development and functionally distinct from hnRNP AB

Andreou, Maria I.; Yan, C. Y. I.; Skourides, Paris A. (2014)

Heterogeneous nuclear ribonucleoproteins (hnRNPs) comprise a large group of modular RNA-binding proteins classified according to their conserved domains. This modular nature, coupled with a large choice of alternative ...

Article

Global dispersal pattern of HIV type 1 subtype CRF01-AE: A genetic trace of human mobility related to heterosexual sexual activities centralized in southeast Asia

Angelis, Konstantinos; Albert, Jan; Mamais, Ioannis A.; Magiorkinis, Gkikas; Hatzakis, Angelos E.; Hamouda, O.; Struck, D.; Vercauteren, J.; Wensing, A. M. J.; Alexiev, Ivailo; Åsjö, Birgitta; Balotta, Claudia; Camacho, Ricardo J.; Coughlan, S.; Griskevicius, A.; Grossman, Z.; Horban, A.; Kostrikis, Leontios G.; Lepej, S.; Liitsola, K.; Linka, M.; Nielsen, C.; Otelea, D.; Paredes, R.; Poljak, M.; Puchhammer-Stöckl, E.; Schmit, J. -C; Sönnerborg, A.; Staneková, D.; Stanojevic, M.; Boucher, C. A. B.; Kaplan, L.; Vandamme, A. -M; Paraskevis, Dimitrios N. (2015)

Background. Human immunodeficiency virus type 1 (HIV-1) subtype CRF01-AE originated in Africa and then passed to Thailand, where it established a major epidemic. Despite the global presence of CRF01-AE, little is known ...

Article

Groucho mediates a Ci-independent mechanism of hedgehog repression in the anterior wing pouch

Apidianakis, Yiorgos; Grbavec, D.; Stifani, S.; Delidakis, Christos (2001)

Groucho (Gro) is the founding member of a family of transcriptional co-repressors that are recruited by a number of different transcription factors. Drosophila has a single gro gene, whose loss of function affects processes ...

Article

Modeling hologenome imbalances in inflammation and cancer

Apidianakis, Yiorgos; Ferrandon, D. (2014)

Book

Model organisms in inflammation and cancer

Apidianakis, Yiorgos; Ferrandon, Dominique (Frontiers Media SA, 2014)

Article

Nest-site preferences of Eleonora's Falcon (Falco eleonorae) on uninhabited islets of the Aegean Sea using GIS and species distribution models

Kassara, Christina; Dimalexis, Anastasios; Fric, Jakob; Karris, Georgios; Barboutis, Christos; Sfenthourakis, Spyros (2012)

Eleonora's Falcon breeds colonially on small islands of the Mediterranean Sea and Macaronesia. Despite the wealth of papers highlighting the importance of nesting characteristics on this species' breeding performance, few ...

Article

A quorum sensing regulated small volatile molecule reduces acute virulence and promotes chronic infection phenotypes

Kesarwani, M.; Hazan, R.; He, J.; Que, Y.; Apidianakis, Yiorgos; Lesic, B.; Xiao, G.; Dekimpe, V.; Milot, S.; Déziel, Eric; Lépine, F.; Rahme, L. G. (2011)

A significant number of environmental microorganisms can cause serious, even fatal, acute and chronic infections in humans. The severity and outcome of each type of infection depends on the expression of specific bacterial ...

Article

Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylation

Kirmizis, Antonis; Santos-Rosa, H.; Penkett, C. J.; Singer, M. A.; Vermeulen, M.; Mann, M.; Bähler, J.; Green, R. D.; Kouzarides, T. (2007)

Modifications on histones control important biological processes through their effects on chromatin structure. Methylation at lysine 4 on histone H3 (H3K4) is found at the 5′ end of active genes and contributes to ...

Article

Diagnostic accuracy of arterial line blood gas measurements as an estimate of arteriovenous fistula recirculation

Kirmizis, Dimitrios; Kougioumtzidou, Ourania; Vakianis, Pantelis (2013)