Browsing by Author "Cervantes, A."
Now showing items 1-15 of 15
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The current and future role of the medical oncologist in the professional care for cancer patients: A position paper by the European Society for Medical Oncology (ESMO)
Popescu, R. A.; Schäfer, R.; Califano, R.; Eckert, R.; Coleman, R.; Douillard, J.-Y.; Cervantes, A.; Casali, Paolo G.; Sessa, Cristiana; Cutsem, E. van; Vries, Elisabeth G. E. de; Pavlidis, Nicholas; Fumasoli, K.; Wörmann, B.; Samonigg, H.; Cascinu, S.; Hernández, J. J. C.; Howard, A. J.; Ciardiello, F.; Stahel, R. A.; Piccart, M. (2014)The number of cancer patients in Europe is rising and significant advances in basic and applied cancer research are making the provision of optimal care more challenging. The concept of cancer as a systemic, highly ...
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The diagnosis and management of gastric cancer: Expert discussion and recommendations from the 12th ESMO/World Congress on Gastrointestinal Cancer, Barcelona, 2010
Cutsem, E. van; Dicato, M.; Geva, R.; Arber, N.; Bang, Y.; Benson, A.; Cervantes, A.; Diaz-Rubio, E.; Ducreux, M.; Glynne-Jones, R.; Grothey, Axel; Haller, D.; Haustermans, K.; Kerr, D.; Nordlinger, B.; Marshall, J.; Minsky, B. D.; Kang, Y. K.; Labianca, R.; Lordick, F.; Ohtsu, A.; Pavlidis, Nicholas; Roth, A.; Rougier, P.; Schmoll, H. J.; Sobrero, A.; Tabernero, Josep; Velde, C. van de; Zalcberg, J. (2011)Well-recognized experts in the field of gastric cancer discussed during the 12th European Society Medical Oncology (ESMO)/World Congress Gastrointestinal Cancer (WCGIC) in Barcelona many important and controversial topics ...
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ESMO consensus conferences: Another source of ESMO clinical practice guidelines
Pavlidis, Nicholas; Stahel, R. A.; Pentheroudakis, George; Cervantes, A. (2012)
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The ESMO guideline strategy: An identity statement and reflections on improvement
Pentheroudakis, George; Cardoso, Fatima; Arnold, D.; Sessa, Cristiana; Peters, S.; Horwich, A.; Pavlidis, Nicholas; Stahel, R. A.; Cervantes, A. (2015)Guidelines should provide recommendations on the optimal management of a patient in specific clinical circumstances based on the scientific evidence. ESMO, as Europe's leading society in medical oncology produces a range ...
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Fourteen years of evolution of ESMO guidelines: From the minimum recommendations to the Consensus Conference-derived guidelines
Pavlidis, Nicholas; Stahel, R. A.; Hansen, H.; Cervantes, A. (2011)
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Immunohistochemical study of the epithelial-mesenchymal transition phenotype in cancer of unknown primary: Incidence, correlations and prognostic utility
Stoyianni, A.; Goussia, Anna; Pentheroudakis, George; Siozopoulou, V.; Ioachim, E.; Krikelis, D.; Golfinopoulos, Vassilis; Cervantes, A.; Bobos, M.; Fotsis, T.; Bellou, S.; Fountzilas, George; Malamou-Mitsi, Vassiliki D.; Pavlidis, Nicholas (2012)Background: The epithelial to mesenchymal transition (EMT) has been associated with metastatic dissemination and poor outcome in several solid tumour types. Our aim was to study its incidence and its prognostic significance ...
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Insights into the epithelial mesenchymal transition phenotype in cancer of unknown primary from a global microRNA profiling study
Stoyianni, A.; Pentheroudakis, George; Benjamin, H.; Cervantes, A.; Ashkenazi, K.; Lazaridis, G.; Pavlidis, Nicholas; Spector, Y. (2014)Purpose: We sought to study the microRNA regulation of epithelial mesenchymal transition (EMT), the acquisition of migratory, mesenchymal-like properties of epithelial cells, in cancer of unknown primary (CUP). Patients ...
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Intracellular signalling via the AKT axis and downstream effectors is active and prognostically significant in cancer of unknown primary (CUP): A study of 100 CUP cases
Golfinopoulos, Vassilis; Pentheroudakis, George; Goussia, Anna; Siozopoulou, V.; Bobos, M.; Krikelis, D.; Cervantes, A.; Ciuleanu, T.; Marselos, M.; Fountzilas, George; Malamou-Mitsi, Vassiliki D.; Pavlidis, Nicholas (2012)Background: Hypothesising that cancer of unknown primary (CUP) may harbour unique characteristics, we present a translational study of the immunohistochemical expression and clinical correlation of key PTEN/AKT pathway ...
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Molecular markers and biological targeted therapies in metastatic colorectal cancer: expert opinion and recommendations derived from the 11th ESMO/World Congress on Gastrointestinal Cancer, Barcelona, 2009.
Cutsem, E. Van; Dicato, M.; Arber, N.; Berlin, J.; Cervantes, A.; Ciardiello, F.; Gramont, A. De; Diaz-Rubio, E.; Ducreux, M.; Geva, R.; Glimelius, B.; Glynne-Jones, R.; Grothey, Axel; Gruenberger, T.; Haller, D.; Haustermans, K.; Labianca, R.; Lenz, H. J.; Minsky, B.; Nordlinger, B.; Ohtsu, A.; Pavlidis, Nicholas; Rougier, P.; Schmiegel, W.; Velde, C. Van de; Schmoll, H. J.; Sobrero, A.; Tabernero, Josep (2010)The article summarizes the expert discussion and recommendations on the use of molecular markers and of biological targeted therapies in metastatic colorectal cancer (mCRC), as well as a proposed treatment decision strategy ...
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Mutational profiling of the RAS, PI3K, MET and b-catenin pathways in cancer of unknown primary: a retrospective study of the Hellenic Cooperative Oncology Group
Pentheroudakis, George; Kotteas, E. A.; Kotoula, V.; Papadopoulou, K.; Charalambous, E.; Cervantes, A.; Ciuleanu, T.; Fountzilas, George; Pavlidis, Nicholas (2014)Cancer of unknown primary origin (CUP) had a poor prognosis, determined by clinico-histological characteristics, partly due to the lack of insights on its biology. We screened tumour DNA from 87 patients with CUP for CTNNB1 ...
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Oncology for medical students:. A European School of Oncology contribution to undergraduate cancer education
Pavlidis, Nicholas; Vermorken, J. B.; Stahel, R. A.; Bernier, J.; Cervantes, A.; Audisio, R.; Pentheroudakis, George; Costa, Alberto (2007)Worldwide undergraduate cancer medicine is taught in a non-unanimous manner. There are frequent overlaps, omissions and discrepancies in the curricula of different medical schools concerning oncology teaching. Various ...
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Profiling clinical cancer research across the Atlantic: A review of research and its characteristics presented at ASCO and ESMO Congresses during the last decade
Pentheroudakis, George; Krikelis, D.; Cervantes, A.; Vermorken, J. B.; Pavlidis, Nicholas (2012)Introduction: The comparison of clinical cancer research characteristics across the Atlantic and their evolution over time have not been studied to date. Methods: We collected oral presentations on breast, lung and colorectal ...
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Profiling immunohistochemical expression of NOTCH1-3, JAGGED1, cMET, and phospho-MAPK in 100 carcinomas of unknown primary
Krikelis, D.; Pentheroudakis, George; Goussia, Anna; Siozopoulou, V.; Bobos, M.; Petrakis, Dimitrios; Stoyianni, A.; Golfinopoulos, Vassilis; Cervantes, A.; Ciuleanu, T.; Fountzilas, George; Malamou-Mitsi, Vassiliki D.; Pavlidis, Nicholas (2012)Cancer of unknown primary (CUP) is a heterogeneous entity, managed on the basis of "one size fits all" therapeutic concepts; insights into the molecular biology of CUP are urgently needed. We retrospectively examined the ...
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Rare Cancers Europe (RCE) methodological recommendations for clinical studies in rare cancers: A European consensus position paper
Casali, Paolo G.; Bruzzi, P.; Bogaerts, Jan; Blay, Jean-Yves; Aapro, M. S.; Adamou, A.; Berruti, A.; Bressington, J.; Bruzzi, B.; Capocaccia, R.; Cardoso, Fatima; Celis, J. E.; Cervantes, A.; Ciardiello, F.; Claussen, C.; Coleman, M.; Comis, S.; Craine, S.; Boltz, D. De; Lorenzo, F. De; P, Angelo Dei Tos; Gatta, G.; Geissler, J.; Giuliani, R.; Grande, E.; Gronchi, A.; Jezdic, S.; Jonsson, B.; Jost, Lorenz M.; Keulen, H.; Lacombe, D.; Lamory, G.; Cam, Y. Le; Priolo, S. Leto di; Licitra, Lisa; Macchia, F.; Margulies, A.; Marreaud, S.; McVie, G.; Narbutas, S.; Oliver, K.; Pavlidis, Nicholas; Pelouchova, J.; Pentheroudakis, George; Piccart, M.; Pierotti, M. A.; Pravettoni, G.; Redmond, K.; Riegman, P.; Ruffilli, M. P.; Ryner, D.; Sandrucci, S.; Seymour, M.; Torri, V.; Trama, A.; Belle, S. Van; Vassal, G.; Wartenberg, M.; Watts, C.; Wilson, A.; Yared, W. (2015)While they account for one-fifth of new cancer cases, rare cancers are difficult to study. A higher than average degree of uncertainty should be accommodated for clinical as well as for population-based decision making. ...
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Undergraduate training in oncology: An ESO continuing challenge for medical students
Pavlidis, Nicholas; Vermorken, J. B.; Stahel, R. A.; Bernier, J.; Cervantes, A.; Pentheroudakis, George; Audisio, R. A.; Costa, Alberto (2012)During the last six years the European School of Oncology (ESO) opened an undergraduate programme for European medical students, aiming to further improve their oncology knowledge and clinical skills. In this endeavour a ...