Browsing by Author "Ioannidis, J. P. A."
Now showing items 1-13 of 13
-
Article
Comparative survival with diverse chemotherapy regimens for cancer of unknown primary site: Multiple-treatments meta-analysis
Golfinopoulos, Vassilis; Pentheroudakis, George; Salanti, G.; Nearchou, A. D.; Ioannidis, J. P. A.; Pavlidis, Nicholas (2009)Objectives: To synthesize the evidence from randomized controlled trials concerning systemic treatment regimens for patients with cancer of unknown primary site (CUP). Data sources: PubMed and the Cochrane Library Central ...
-
Article
Effects of CCR5-Δ32, CCR2-64I, and SDF-1 3′ a alleles on HIV-1 disease progression: An international meta-analysis of individual-patient data
Ioannidis, J. P. A.; Rosenberg, P. S.; Goedert, J. J.; Ashton, L. J.; Benfield, T. L.; Buchbinder, S. P.; Coutinho, R. A.; Eugen-Olsen, J.; Gallart, T.; Katzenstein, T. L.; Kostrikis, Leontios G.; Kuipers, H.; Louie, L. G.; Mallal, S. A.; Margolick, J. B.; Martinez, O. P.; Meyer, L.; Michael, N. L.; Operskalski, E.; Pantaleo, G.; Rizzardi, G. P.; Schuitemaker, H.; Sheppard, H. W.; Stewart, G. J.; Theodorou, I. D.; Ullum, H.; Vicenzi, E.; Vlahov, D.; Wilkinson, D.; Workman, C.; Zagury, J. -F; O'Brien, T. R. (2001)Background: Studies relating certain chemokine and chemokine receptor gene alleles with the outcome of HIV-1 infection have yielded inconsistent results. Objective: To examine postulated associations of genetic alleles ...
-
Article
Effects of different chemotherapy regimens on survival for advanced cervical cancer: Systematic review and meta-analysis
Tzioras, S.; Pavlidis, Nicholas; Paraskevaidis, E.; Ioannidis, J. P. A. (2007)Background: A large number of trials have assessed various chemotherapy regimens for the treatment of advanced cervical cancer, but there is uncertainty about the magnitude of survival benefits. Methods: We searched (last ...
-
Article
Levels of absolute survival benefit for systemic therapies of advanced cancer: A call for standards
Ioannidis, J. P. A.; Pavlidis, Nicholas (2003)Research on systemic interventions in patients with advanced stage malignancies should be systematised with an emphasis on the absolute gain in survival for the median patient. Such information is most meaningful with ...
-
Article
Multiple-treatments meta-analysis of chemotherapy and targeted therapies in advanced breast cancer
Mauri, D.; Polyzos, N. P.; Salanti, G.; Pavlidis, Nicholas; Ioannidis, J. P. A. (2008)Background: Many systemic nonhormonal regimens have been evaluated across several hundreds of randomized trials in advanced breast cancer. We aimed to quantify the relative merits of these regimens in prolonging survival. ...
-
Article
Neoadjuvant versus adjuvant systemic treatment in breast cancer: A meta-analysis
Mauri, D.; Pavlidis, Nicholas; Ioannidis, J. P. A. (2005)Background: Interest in the use of preoperative systemic treatment in the management of breast cancer has increased because such neoadjuvant therapy appears to reduce the extent of local surgery required. We compared the ...
-
Article
Randomised trials comparing chemotherapy regimens for advanced non-small cell lung cancer: Biases and evolution over time
Ioannidis, J. P. A.; Polycarpou, A.; Ntais, C.; Pavlidis, Nicholas (2003)We systematically evaluated the evidence from randomised trials comparing various chemotherapy regimens for advanced non-small cell lung cancer. Across 254 eligible trials (42 661 patients), no regimens were compared in ...
-
Article
Randomized evidence on chemotherapy and hormonal therapy regimens for advanced endometrial cancer: An overview of survival data
Polyzos, N. P.; Pavlidis, Nicholas; Paraskevaidis, E.; Ioannidis, J. P. A. (2006)Several chemotherapy and hormonal therapy regimens have been used in advanced endometrial cancer. In this review we have systematically evaluated the available data from randomized trials on survival. We searched MEDLINE, ...
-
Article
Re: Neoadjuvant versus adjuvant systemic treatment in breast cancer: A meta-analysis (multiple letters) [2]
Popat, S.; Smith, I. E.; Mauri, D.; Pavlidis, Nicholas; Ioannidis, J. P. A. (2005)
-
Article
Response
Ioannidis, J. P. A.; Mauri, D.; Polyzos, N. P.; Pavlidis, Nicholas (2007)
-
Article
Survival and disease-progression benefits with treatment regimens for advanced colorectal cancer: a meta-analysis
Golfinopoulos, Vassilis; Salanti, G.; Pavlidis, Nicholas; Ioannidis, J. P. A. (2007)Background: Many randomised trials have compared different systemic treatment regimens in patients with advanced colorectal cancer. While survival advances have apparently been achieved, the magnitude of these incremental ...
-
Article
Survival benefits with diverse chemotherapy regimens for ovarian cancer: Meta-analysis of multiple treatments
Kyrgiou, M.; Salanti, G.; Pavlidis, Nicholas; Paraskevaidis, E.; Ioannidis, J. P. A. (2006)Background: Numerous randomized trials have compared different chemotherapy regimens in women with ovarian cancer. Although ovarian cancer survival has improved in recent years, the magnitude of these incremental benefits ...
-
Article
Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: Meta-analysis
Mauri, D.; Pavlidis, Nicholas; Polyzos, N. P.; Ioannidis, J. P. A. (2006)Background: Aromatase inhibitors and inactivators have been extensively tested in patients with advanced breast cancer, but it is unclear whether they offer any survival benefits compared with standard hormonal treatment ...