Browsing by Author "Pavlakis, G. N."
Now showing items 1-2 of 2
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Article
CXCR4 mediates entry and productive infection of syncytia-inducing (x4) hiv-1 strains in primary macrophages
Valentin, A.; Trivedi, H.; Lu, W.; Kostrikis, Leontios G.; Pavlakis, G. N. (2000)CCR5 and CXCR4 are the main coreceptors for non-syncytia-inducing (NSI) and syncytia-inducing (SI) HIV-1 strains, respectively. NSI HIV-1 isolates do not infect either human lymphoid or monocytoid cell lines, and this ...
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Article
Persistent HIV-1 infection of natural killer cells in patients receiving highly active antiretroviral therapy
Valentin, A.; Rosati, M.; Patenaude, D. J.; Hatzakis, Angelos E.; Kostrikis, Leontios G.; Lazanas, Marios C.; Wyvill, K. M.; Yarchoan, R.; Pavlakis, G. N. (2002)We have identified a subset of CD56+CD3- human natural killer (NK) cells that express CD4 and the HIV coreceptors CCR5 and CXCR4. These cells can be productively infected in vitro by both CCR5- and CXCR4-using molecular ...