Browsing by Author "Pentheroudakis, George"
Now showing items 1-20 of 104
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Axillary nodal metastases from carcinoma of unknown primary (CUPAx): A systematic review of published evidence
Pentheroudakis, George; Lazaridis, G.; Pavlidis, Nicholas (2010)Axillary lymph node metastases from adenocarcinoma or poorly differentiated carcinoma of unknown primary (CUPAx) represent a rare clinical entity without consensus on its biology, management and outcome. We systematically ...
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Biomarkers of benefit from cetuximab-based therapy in metastatic colorectal cancer: Interaction of EGFR ligand expression with RAS/RAF, PIK3CA genotypes
Pentheroudakis, George; Kotoula, V.; Roock, W. De; Kouvatseas, G.; Papakostas, P.; Makatsoris, T.; Papamichael, D.; Xanthakis, I.; Sgouros, J.; Televantou, D.; Kafiri, G.; Tsamandas, A. C.; Razi, E. D.; Galani, E.; Bafaloukos, Dimitrios; Efstratiou, I.; Bompolaki, I.; Pectasides, Dimitrios; Pavlidis, Nicholas; Tejpar, S.; Fountzilas, George (2013)Background: More than half of patients with KRAS-wild type advanced colorectal cancer (CRC) fail anti-EGFR monoclonal antibodies. We studied EGFR-axis messenger RNA (mRNA) expression and RAS, RAF, PIK3CA mutations in order ...
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Biweekly administration of 24-h infusion of irinotecan followed by a 1-h infusion of docetaxel: A phase I study
Briassoulis, E. Ch; Pentheroudakis, George; Timotheadou, H.; Rammou, D.; Pavlidis, Nicholas; Fountzilas, George (2004)We developed a chemotherapy combination regimen based on preclinical data suggesting synchronization of cancer cells in G2/M phase when exposed to irinotecan over a protracted period. This phase I study aimed to determine ...
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Can circulated lung cancer cells pass to the urine without apparent urine tract metastases?. A single centre series
Kamposioras, K.; Pentheroudakis, George; Malamou-Mitsi, Vassiliki D.; Pappa, L.; Bafa, M.; Pavlidis, Nicholas (2008)Urine cytology has been a useful tool for the diagnosis of urinary tract malignancies. However, the presence of tumor cells in the urine sediment without an obvious urothelial metastatic deposit is a rare phenomenon and ...
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Cancer and pregnancy: A comprehensive review
Voulgaris, E.; Pentheroudakis, George; Pavlidis, Nicholas (2011)Background: Pregnancy complicated by cancer is relatively rare but, as women in western societies tend to delay childbearing to the third and fourth decade of life, this phenomenon is going to be encountered more often in ...
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Cancer and pregnancy: Poena magna, not anymore
Pentheroudakis, George; Pavlidis, Nicholas (2006)Cancer diagnosed during pregnancy constitutes a difficult clinical condition with a devastating impact on the patient's somatic and psychosocial health and possibly on foetal integrity. This circumstance also raises several ...
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Cancer diagnosis in a cohort of patients with Sjogren's syndrome and rheumatoid arthritis: A single-center experience and review of the literature
Boussios, Stergios; Pentheroudakis, George; Somarakis, G.; Markatseli, T. E.; Drosos, Alexandros A.; Pavlidis, Nicholas (2014)Background: With the development of modern therapies and better care of patients with autoimmune rheumatic diseases (ARDs) increased survival has been achieved. However, ARDs may share an association with risk of lymphomas ...
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Cancer of Unknown Primary origin in the genomic era: Elucidating the dark box of cancer
Economopoulou, P.; Mountzios, G.; Pavlidis, Nicholas; Pentheroudakis, George (2015)Cancer of Unknown Primary (CUP) comprises a heterogeneous disease group with diagnosis of metastatic malignancy in the absence of an identifiable primary site after diagnostic work up. CUP may either resemble a specific ...
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Cancer of unknown primary patients with midline nodal distribution: Midway between poor and favourable prognosis?
Pentheroudakis, George; Stoyianni, A.; Pavlidis, Nicholas (2011)Background: Midline nodal cancer of unknown primary (CUP) has varying definitions and an unclear natural history compared to that of extragonadal germ cell cancer (EGCC) and neuroendocrine tumors. Methods: We systematically ...
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Cancer of unknown primary site
Pavlidis, Nicholas; Pentheroudakis, George (2012)Cancer of unknown primary site (CUP) is a well recognised clinical disorder, accounting for 3-5 of all malignant epithelial tumours. CUP is clinically characterised as an aggressive disease with early dissemination. ...
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Cancer of unknown primary site: 20 questions to be answered
Pavlidis, Nicholas; Pentheroudakis, George (2010)Cancer of unknown primary (CUP) is a common, well-recognized and heterogeneous clinical syndrome. Patients with CUP present with metastatic disease in the absence of an identifiable primary tumour despite a diagnostic ...
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Cancer of unknown primary site: Missing primary or missing biology?
Pentheroudakis, George; Briassoulis, E. Ch; Pavlidis, Nicholas (2007)Cancer of unknown primary site (CUP) ranks as the fourth most common cause of cancer deaths and represents both a diagnostic and a management challenge. In CUP, the regression or dormancy of the primary tumor, the development ...
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Cancer of unknown primary: What kind of chemotherapy? what kind of disease?
Pentheroudakis, George; Pavlidis, Nicholas (2009)
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Cancer, fertility and pregnancy: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Pentheroudakis, George; Orecchia, R.; Hoekstra, H. J.; Pavlidis, Nicholas (2010)
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Cancer, fertility and pregnancy: ESMO Clinical Recommendations for diagnosis, treatment and follow-up
Pentheroudakis, George; Pavlidis, Nicholas; Castiglione, M. (2009)
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Cancer, fertility and pregnancy: ESMO clinical recommendations for diagnosis, treatment and follow-up
Pentheroudakis, George; Pavlidis, Nicholas; Castiglione, M. (2008)
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Cancer, pregnancy and fertility: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Peccatori, Fedro A.; Azim, Hatem A.; Orecchia, R.; Hoekstra, H. J.; Pavlidis, Nicholas; Kesic, V.; Pentheroudakis, George (2013)
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Cancers of unknown primary site: ESMO clinical practice guidelines for diagnosis, treatment and follow-up
Pavlidis, Nicholas; Briassoulis, E. Ch; Pentheroudakis, George (2010)
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Cancers of unknown primary site: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Fizazi, K.; Greco, F. A.; Pavlidis, Nicholas; Daugaard, G.; Oien, K.; Pentheroudakis, George; ESMO Guidelines Committee (2015)
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Cancers of unknown primary site: ESMO clinical practice guidelines for diagnosis, treatment and follow-up
Fizazi, K.; Greco, F. A.; Pavlidis, Nicholas; Pentheroudakis, George (2011)