Browsing by Author "Tsiara, Chrissa G."
Now showing items 1-17 of 17
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The association between plasminogen activator inhibitor type 1 (PAI-1) levels, PAI-1 4G/5G polymorphism, and myocardial infarction: A mendelian randomization meta-analysis
Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Tsangaris, I.; Tsiara, Chrissa G.; Kopterides, Petros; Vaiopoulos, A.; Kapsimali, Violetta; Bonovas, Stefanos; Tsantes, Argirio E. (2014)Background: The circulating levels of plasminogen activator inhibitor type 1 (PAI-1) are increased in individuals carrying the 4G allele at position -675 of the PAI-1 gene. In turn, overexpression of PAI-1 has been found ...
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Association between the plasminogen activator inhibitor-1 4G/5G gene polymorphism and ischemic stroke; A meta-analysis.
Nikolopoulos, Georgios K.; Tsantes, Argirio E.; Bagos, Pantelis G.; Tsiara, Chrissa G.; Mantzios, Georgios P.; Kapsimali, Violetta; Pappa, Vassiliki; Travlou, Anthi S. (2006)
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Condom effectiveness in reducing heterosexual HIV transmission: a systematic review and meta-analysis of studies on HIV serodiscordant couples
Giannou, Foteini K.; Tsiara, Chrissa G.; Nikolopoulos, Georgios K.; Talias, M.; Benetou, Vasiliki; Kantzanou, Maria; Bonovas, Stefanos; Hatzakis, A. (2016)Objective: This systematic review and meta-analysis aimed to reassess the effectiveness of condoms in reducing heterosexual transmission of HIV. Methods: Medline, Scopus, and the ISI Web of Science databases were searched ...
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Cytokine gene polymorphisms in multiple sclerosis: A meta-analysis of 45 studies including 7379 cases and 8131 controls
Nikolopoulos, Georgios K.; Masgala, Aikaterini; Tsiara, Chrissa G.; Limitsiou, O. K.; Karnaouri, Anthi C.; Dimou, Niki L.; Bagos, Pantelis G. (2011)Many environmental and genetic factors have been implicated in the development of multiple sclerosis. However, the aetiology has not been clarified yet. Therefore, using a meta-analytic approach, we tried to probe the ...
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Design and baseline findings of a large-scale rapid response to an HIV outbreak in people who inject drugs in Athens, Greece: The ARISTOTLE programme
Hatzakis, A.; Sypsa, V.; Paraskeva, D.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Micha, Katerina; Panopoulos, A.; Malliori-Minerva, Melpomeni; Psichogiou, M.; Pharris, Anastasia; Wiessing, L.; Laar, M. J. van de; Donoghoe, Martin; Heckathorn, Douglas D.; Friedman, Samuel R.; Jarlais, Don C. Des (2015)Aims: To (i) describe an intervention implemented in response to the HIV-1 outbreak among people who inject drugs (PWIDs) in Greece (ARISTOTLE programme), (ii) assess its success in identifying and testing this population ...
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Economic recession and emergence of an HIV-1 outbreak among drug injectors in Athens metropolitan area: A longitudinal study
Paraskeva, D.; Nikolopoulos, Georgios K.; Fotiou, Anastasios; Tsiara, Chrissa G.; Paraskeva, D.; Sypsa, V.; Lazanas, Marios; Gargalianos, Panagiotis; Psichogiou, M.; Skoutelis, A.; Wiessing, L.; Friedman, Samuel R.; Jarlais, Don C. Des; Terzidou, M.; Kremastinou, Jenny; Malliori-Minerva, Melpomeni; Hatzakis, A. (2013)Background: During 2011, a dramatic increase (1600%) of reported HIV-1 infections among injecting drug users (IDUs) was noted in Athens, Greece. We herein assess the potential causal pathways associated with this outbreak. ...
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Effect of hepatitis C virus on immunological and virological responses in HIV-infected patients initiating highly active antiretroviral therapy: A meta-analysis
Tsiara, Chrissa G.; Nikolopoulos, Georgios K.; Dimou, Niki L.; Bagos, Pantelis G.; Saroglou, G.; Velonakis, E.; Hatzakis, A. (2013)Co-infection of human immunodeficiency virus (HIV) with hepatitis C virus (HCV) is rather common. In the era of highly active antiretroviral therapy (HAART), viral hepatitis could result in adverse outcomes in HIV+ patients. ...
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Enhanced HIV-1 surveillance using molecular epidemiology to study and monitor HIV-1 outbreaks among intravenous drug users (IDUs) in Athens and Bucharest
Paraskeva, D.; Paraschiv, S.; Sypsa, V.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Magiorkinis, Gkikas; Psichogiou, M.; Flampouris, Andreas; Mardarescu, Mariana; Niculescu, I.; Batan, Ionelia; Malliori-Minerva, Melpomeni; Otelea, D.; Hatzakis, A. (2015)Background: A significant increase in HIV-1 diagnoses was reported among Injecting Drug Users (IDUs) in the Athens (17-fold) and Bucharest (9-fold) metropolitan areas starting 2011. Methods: Molecular analyses were conducted ...
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Evaluation of the limiting antigen avidity EIA (LAg) in people who inject drugs in Greece
Nikolopoulos, Georgios K.; Katsoulidou, Antigoni; Kantzanou, Maria; Rokka, C.; Tsiara, Chrissa G.; Sypsa, V.; Paraskeva, D.; Psichogiou, M.; Friedman, Samuel R.; Hatzakis, A. (2017)This analysis assessed the utility of the limiting antigen avidity assay (LAg). Samples of people who inject drugs (PWID) in Greece with documented duration of HIV-1 infection were tested by LAg. A LAg-normalized optical ...
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HIV-1 outbreak among injecting drug users in Greece, 2011: A preliminary report
Paraskeva, D.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Paraskeva, D.; Antoniadou, Anastasia; Lazanas, Marios; Gargalianos, Panagiotis; Psychogiou, M.; Malliori-Minerva, Melpomeni; Kremastinou, Jenny; Hatzakis, A. (2011)A significant increase (more than 10-fold) in the number of newly diagnosed HIV-1 infections among injecting drug users (IDUs) was observed in Greece during the first seven months of 2011. Molecular epidemiology results ...
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Impact of HIV type 1 DNA levels on spontaneous disease progression: A meta-analysis
Tsiara, Chrissa G.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Goujard, Cecile; Katzenstein, Terese L.; Minga, Albert K.; Rouzioux, C.; Hatzakis, A. (2012)Several studies have reported the prognostic strength of HIV-1 DNA with variable results however. The aims of the current study were to estimate more accurately the ability of HIV-1 DNA to predict progression of HIV-1 ...
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The implementation of EPP software using HIV prevalence data from studies conducted in Greece
Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Botsi, Chryssoula (2010)An abstract of the article "The implementation of EPP software using HIV prevalence data from studies conducted in Greece," by Georgios Nikolopoulos, Chryssa Tsiara and Chryssoula Botsi is presented.
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Interleukin gene polymorphisms and susceptibility to HIV-1 infection: a meta-analysis
Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Dimou, Niki L.; Pantavou, Katerina G.; Bagos, Pantelis G.; Mensah, Benedicta; Talias, Michael; Braliou, Georgia G.; Paraskeva, Dimitra; Bonovas, Stefanos; Hatzakis, Angelos (2018)Some subjects are repeatedly exposed to human immunodeficiency virus (HIV), yet they remain uninfected. This suggests the existence of host-resistance mechanisms. The current study synthesizes the evidence regarding the ...
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Plasminogen activator inhibitor-1 4G/5G polymorphism and risk of ischemic stroke: A meta-analysis
Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Tsiara, Chrissa G.; Kapsimali, Violetta; Travlou, Anthi S.; Vaiopoulos, G. (2007)This study investigated the hypothesis that the insertion/deletion (4G/5G) polymorphism of the plasminogen activator inhibitor type-1 gene affects the risk for ischemic stroke, since results concerning this association ...
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Post-exposure prophylaxis after non-occupational exposure to HIV in Greece
Raftopoulos, V.; Nikolopoulos, Georgios K.; Konte, Vasileia; Pylli, M.; Tsiara, Chrissa G.; Makri, Efraxia; Paraskeva, D. (2008)Aim: To assess the use of post-exposure prophylaxis after a non-occupational exposure to HIV in Greece. Methods: We analysed the data that were reported to the Hellenic Centre for Disease Control and Prevention by physicians ...
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Rapid Decline in HIV Incidence among Persons Who Inject Drugs during a Fast-Track Combination Prevention Program after an HIV Outbreak in Athens
Sypsa, V.; Psichogiou, M.; Paraskeva, D.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Paraskeva, D.; Micha, Katerina; Malliori-Minerva, Melpomeni; Pharris, Anastasia; Wiessing, L.; Donoghoe, Martin; Friedman, Samuel R.; Jarlais, Don Des; Daikos, Georgios L.; Hatzakis, A. (2017)Background. A "seek-test-treat" intervention (ARISTOTLE) was implemented in response to an outbreak of human immunodeficiency virus (HIV) infection among persons who inject drugs (PWID) in Athens. We assess trends in HIV ...
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Surveillance of HIV exposure and postexposure prophylaxis among health care workers in Greece
Konte, Vasileia; Nikolopoulos, Georgios K.; Raftopoulos, V.; Pylli, M.; Tsiara, Chrissa G.; Makri, Efraxia; Paraskeva, D. (2007)Objective: Many developed countries have implemented surveillance systems for monitoring occupational exposure to HIV. The aim of the present study was to analyze surveillance data on HIV postexposure prophylaxis (PEP) for ...