Browsing by Subject "Genetic susceptibility"
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Article
The complex pathogenesis of bacteremia: From antimicrobial clearance mechanisms to the genetic background of the host
(2014)Bacteremia develops when bacteria manage to escape the host immune mechanisms or when the otherwise well-orchestrated immune response fails to control bacterial spread due to inherent or acquired immune defects that are ...
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Article
The effect of the plasminogen activator inhibitor-1 4G/5G polymorphism on the thrombotic risk
(2008)Plasminogen activator inhibitor (PAI-1), is the central component of the fibrinolytic system. A deletion/insertion (4G/5G) polymorphism in the promoter region of the PAI-1 gene has been correlated with levels of plasma ...
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Article
The GNB3 C825T polymorphism and essential hypertension: A meta-analysis of 34 studies including 14 094 cases and 17 760 controls
(2007)OBJECTIVES: The C825T single nucleotide polymorphism of the G-protein β3 (GNB3) has been implicated in susceptibility to essential hypertension, through the expression of an alternatively spliced truncated variant. In an ...