• Article  

      Changing stem cell dynamics during papillomavirus infection: Potential roles for cellular plasticity in the viral lifecycle and disease 

      Strati, Katerina (2017)
      Stem cells and cellular plasticity are likely important components of tissue response to infection. There is emerging evidence that stem cells harbor receptors for common pathogen motifs and that they are receptive to local ...
    • Master Thesis  Open Access

      The HPV16 E6 and E7 oncogenes modify Glutamine metabolism in Cervical Cancers 

      Andreou, Vasiliki (Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2023-05-18)
      Metabolic reprogramming is an established hallmark of cancer. Malignant cells induce metabolic adjustments to meet their high energy demands and sustain rapid proliferation. These metabolic changes involve modifications ...
    • Article  

      The HPV16 oncogenes cause aberrant stem cell mobilization 

      Michael, S.; Lambert, P. F.; Strati, Katerina (2013)
      Human Papilloma Virus related epithelial cancers have been speculated to derive from virus-infected tissue stem cells. Stem cells also are thought to provide a reservoir of latently infected cells that can persist for long ...
    • Article  

      Human papillomavirus association with head and neck cancers: Understanding virus biology and using it in the development of cancer diagnostics 

      Strati, Katerina; Lambert, P. F. (2008)
      The link between human papillomaviruses (HPVs) and human cervical cancers has long been established. However, HPVs are now being detected in another type of cancer not previously associated with this virus, head and neck ...
    • Doctoral Thesis  Open Access

      Mouse models for papillomavirus-mediated phenotypes 

      Achilleos, Charis A. (Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2018-07)
      Οι HPV έχουν συσχετιστεί με την ανάπτυξη της πλειονότητας των καρκίνων του τραχήλου της μήτρας, καθώς και με ένα υποσύνολο καρκίνου κεφαλής και λαιμού, καρκίνο του δέρματος και άλλων καρκίνων της γενετικής περιοχής. Στόχος ...
    • Article  

      Shared mechanisms in stemness and carcinogenesis: Lessons from oncogenic viruses 

      Iacovides, D.; Michael, S.; Achilleos, Charis; Strati, Katerina (2013)
      A rise in technologies for epigenetic reprogramming of cells to pluripotency, highlights the potential of understanding and manipulating cellular plasticity in unprecedented ways. Increasing evidence points to shared ...