Browsing by Subject "Hydroxymethylglutaryl coenzyme a reductase inhibitor"

Article

Can statin therapy reduce the risk of melanoma? A meta-analysis of randomized controlled trials

Bonovas, Stefanos; Nikolopoulos, Georgios K.; Filioussi, K.; Peponi, Evangelia; Bagos, Pantelis G.; Sitaras, N. M. (2010)

A growing body of literature suggests that statins may have a chemopreventive potential against melanoma through pleiotropic anti-inflammatory, immunomodulatory, and antiangiogenesis mechanisms. Our aim was to examine this ...

Article

Developing the evidence base for cancer chemoprevention: Use of meta-analysis

Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Bonovas, Stefanos (2011)

Meta-analysis is a quantitative approach for systematically combining the results of previous studies in order to arrive at conclusions about the body of research. It answers a specific research question, includes an ...

Article

Efficacy and safety of more intensive lowering of LDL cholesterol [1]

Bonovas, Stefanos; Nikolopoulos, Georgios K.; Sitaras, N. M. (2011)

Article

Immunomodulatory therapy for sepsis: An update

Christaki, Eirini; Anyfanti, Panagiota; Opal, Steven M. (2011)

Currently the treatment mainstay of sepsis is early and appropriate antibiotic therapy, accompanied by aggressive fluid administration, the use of vasopressors when needed and the prompt initiation of measures to support ...

Article

Statins and reduced risk of hepatocellular carcinoma in patients with hepatitis C virus infection: Further evidence is warranted

Bonovas, Stefanos; Sitaras, N. M.; Nikolopoulos, Georgios K. (2013)

Article

Statins and the risk of colorectal cancer: An updated systematic review and meta-analysis of 40 studies

Lytras, Theodoros; Nikolopoulos, Georgios K.; Bonovas, Stefanos (2014)

Aim: To investigate the association between statin use and colorectal cancer risk, we conducted an updated meta-analysis of published studies. Methods: We performed a comprehensive search for studies published up to July ...