Browsing by Subject "Immune response"
Now showing items 1-11 of 11
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Apoptosis and hepatitis C virus infection in renal transplant recipients
(2008)Hepatocellular injury in renal transplant recipients with hepatitis C virus (HCV) infection remains unclear. The suppressed immune response, in combination with increased viremia levels, provides a unique setting for the ...
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The complex pathogenesis of bacteremia: From antimicrobial clearance mechanisms to the genetic background of the host
(2014)Bacteremia develops when bacteria manage to escape the host immune mechanisms or when the otherwise well-orchestrated immune response fails to control bacterial spread due to inherent or acquired immune defects that are ...
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Cytokine gene polymorphisms in multiple sclerosis: A meta-analysis of 45 studies including 7379 cases and 8131 controls
(2011)Many environmental and genetic factors have been implicated in the development of multiple sclerosis. However, the aetiology has not been clarified yet. Therefore, using a meta-analytic approach, we tried to probe the ...
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A fragment of the alarmin prothymosin α as a novel biomarker in murine models of bacteria-induced sepsis
(2017)Sepsis is a life-threatening condition that requires urgent care. Thus, the identification of specific and sensitive biomarkers for its early diagnosis and management are of clinical importance. The alarmin prothymosin ...
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Host immune response in sepsis due to ventilator-associated pneumonia: How is it different?
(2009)Current evidence regarding potentially different host response mechanisms in sepsis according to the type of initiating infection is sporadic. It is possible that alterations in cell populations, variations in effector ...
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Intratumoral CRH modulates immuno-escape of ovarian cancer cells through FasL regulation
(2007)Although corticotropin-releasing hormone (CRH) and Fas ligand (FasL) have been documented in ovarian carcinoma, a clear association with tumour progression and immuno-escape has not been established. FasL plays an important ...
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Local immune response after intravesical interferon gamma in superficial bladder cancer
(1998)To investigate the lymphocyte subpopulations (T4, T8 and macrophages) and major histocompatibility (MHC) II antigens in patients with superficial bladder cancer before and after intravesicai instillations of recombinant ...
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Predictors of humoral response to recommended vaccines in HIV-infected adults
(2017)Humoral response to vaccination has been found to be inadequate in individuals infected with the human immunodeficiency virus (HIV). We retrospectively assessed antibody responses to three routinely recommended vaccines, ...
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Prognostic factors in aggressive non-Hodgkin's lymphomas
(1998)Aggressive non-Hodgkin's lymphoma (NHL) is a biologically heterogeneous disease that can be cured with aggressive chemotherapy treatment. Different clinical, biological, cellular and molecular features have been identified ...
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Role of vascular normalization in benefit from metronomic chemotherapy
(2017)Metronomic dosing of chemotherapy - defined as frequent administration at lower doses - has been shown to be more efficacious than maximum tolerated dose treatment in preclinical studies, and is currently being tested in ...
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Specific antibody to Cryptococcus neoformans glucurunoxylomannan antagonizes antifungal drug action against cryptococcal biofilms in vitro
(2006)The fungus Cryptococcus neoformans possesses a polysaccharide capsule and can form biofilms on medical devices. We investigated the efficacy that the combination of a specific antibody to the capsular polysaccharide and ...