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Browsing by Subject "Proportional hazards models"

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    • Article  

      Age-Dependent Metastatic Spread and Survival: Cancer of Unknown Primary as a Model 

      Hemminki, K.; Pavlidis, Nicholas; Tsilidis, K. K.; Sundquist, K.; Ji, J. (2016)
      In order to describe a novel approach for the clinical study of metastases, we provide here age-specific incidence and survival data for cancer of unknown primary (CUP). Metastases in various organs are found at CUP ...

    • Article  

      Chemotherapy for patients with two favourable subsets of unknown primary carcinoma: Active, but how effective? 

      Pentheroudakis, George; Briassoulis, E. Ch; Karavasilis, V.; Fountzilas, George; Xeros, N.; Samelis, G.; Samantas, E.; Pavlidis, Nicholas (2005)
      Carcinoma of unknown primary (CUP) is characterized by dismal patient survival. The outcome of patients with two favourable risk CUP subsets was studied. Eighty patients diagnosed with either midline lymph node metastases ...

    • Article  

      Liver metastases from cancer of unknown primary (CUPL): A retrospective analysis of presentation, management and prognosis in 49 patients and systematic review of the literature 

      Lazaridis, G.; Pentheroudakis, George; Fountzilas, George; Pavlidis, Nicholas (2008)
      Aim: Patients with liver metastases from cancer of unknown primary (CUPL) have a dismal prognosis. We retrospectively analysed their management and outcome and performed a systematic review of CUPL series published in the ...

    • Article  

      Low-grade mucosa-associated lymphoid tissue lymphoma: A retrospective analysis of 97 patients by the Hellenic Cooperative Oncology Group (HeCOG) 

      Papaxoinis, G.; Fountzilas, George; Rontogianni, D.; Dimopoulos, M. A.; Pavlidis, Nicholas; Tsatalas, C.; Pectasides, Dimitrios; Xiros, N.; Economopoulos, T. (2008)
      Background: The aim was to examine characteristics and treatment results of patients with mucosa-associated lymphoid tissue (MALT) non-Hodgkin's lymphomas. Patients and methods: Epidemiological and clinical features of 97 ...

    • Article  

      Metabolic syndrome and its components as predictors of ischemic stroke in type 2 diabetic patients 

      Protopsaltis, I. D.; Korantzopoulos, Panagiotis; Milionis, Haralampos J.; Koutsovasilis, Anastasios; Nikolopoulos, Georgios K.; Dimou, Eftihia; Kokkoris, Stelios; Brestas, Paris; Elisaf, Moses S.; Melidonis, Andreas (2008)
      BACKGROUND AND PURPOSE - The available data regarding the association between metabolic syndrome (MS) or MS components and ischemic stroke in type 2 diabetics are limited and inconsistent. This study aimed to investigate ...

    • Article  

      Prognostic significance of RACGAP1 mRNA expression in high-risk early breast cancer: A study in primary tumors of breast cancer patients participating in a randomized Hellenic Cooperative Oncology Group trial 

      Pliarchopoulou, K.; Kalogeras, K. T.; Kronenwett, R.; Wirtz, R. M.; Eleftheraki, A. G.; Batistatou, Anna; Bobos, M.; Soupos, N.; Polychronidou, G.; Gogas, H.; Samantas, E.; Christodoulou, C.; Makatsoris, T.; Pavlidis, Nicholas; Pectasides, Dimitrios; Fountzilas, George (2013)
      Purpose: RACGAP1 is a Rac GTPase-activating protein involved in cell growth regulation, cell transformation and metastasis. The aim of the present study was to explore the prognostic and/or predictive significance of RACGAP1 ...

    • Article  

      Prognostic significance of UBE2C mRNA expression in high-risk early breast cancer. A hellenic cooperative oncology group (HECOG) study 

      Psyrri, A.; Kalogeras, K. T.; Kronenwett, R.; Wirtz, R. M.; Batistatou, Anna; Bournakis, E.; Timotheadou, E.; Gogas, H.; Aravantinos, Gerasimos; Christodoulou, C.; Makatsoris, T.; Linardou, H.; Pectasides, Dimitrios; Pavlidis, Nicholas; Economopoulos, T.; Fountzilas, George (2012)
      Background: The ubiquitin-proteasome system (UPS) plays a pivotal role in tumorigenesis. Components of the UPS have recently been implicated in breast cancer progression. In the present study, we sought to explore the ...

    • Article  

      Statistical modelling and prognostic analysis in primary breast carcinoma 

      Vonta, Filia; Karagrigoriou, Alex; Adamou, Adamos K.; Zouvani, Ioanna; Kyriacou, Kyriacos C. (2000)
      This work reports, for the first time, the results of the first retrospective study on breast cancer in Cyprus. The study which is based on 197 women with primary breast cancer who have undergone modified radical mastectomy ...

    • Article  

      Survival estimation through the cumulative hazard function with monotone natural cubic splines 

      Bantis, Leonidas; Tsimikas, John; Georgiou, Stelios N. (Springer Science & Business Media B.V, 2012)
      In this paper we explore the estimation of survival probabilities via a smoothed version of the survival function, in the presence of censoring. We investigate the fit of a natural cubic spline on the cumulative hazard ...

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