Browsing by Subject "Risk factors"

Article

Alcohol and psychoactive drugs increased the pre-hospital mortality in 655 fall-related fatalities in Greece: A call for management protocols

Papadopoulos, I. N.; Bonovas, Stefanos; Kanakaris, Nikolaos K.; Nikolopoulos, Georgios K.; Kotsilianou, Olympia; Konstantoudakis, Georgios; Leukidis, Christos (2012)

Introduction: The frequency of alcohol and psychoactive drugs in fall-related fatalities and their effect on type, severity of injury and location of death constitute the subjects of this study. Methods: A retrospective ...

Article

Association between the plasminogen activator inhibitor-1 4G/5G polymorphism and venous thrombosis

Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Rapti, E.; Mantzios, Georgios P.; Kapsimali, Violetta; Travlou, Anthi S. (2007)

The effect of the 675 insertion/deletion (4G/5G) polymorphism of plasminogen activator inhibitor-1 (PAI-1) gene on the risk of venous thromboembolism (VTE) remains controversial. In this study, we performed a meta-analysis ...

Article

Carcinoma of unknown primary (CUP)

Pavlidis, Nicholas; Fizazi, K. (2009)

Carcinoma of unknown primary (CUP) is one of the 10 most frequent cancers worldwide. It constitutes 3-5% of all human malignancies. Patients with CUP present with metastases without an established primary site. CUP manifests ...

Article

Cefditoren: Comparative efficacy with other antimicrobials and risk factors for resistance in clinical isolates causing UTIs in outpatients

Hatzaki, Despina; Poulakou, G.; Katsarolis, Ioannis; Lambri, Niki; Souli, M.; Deliolanis, Ioannis; Nikolopoulos, Georgios K.; Lebessi, Evangelia; Giamarellou, Helen (2012)

Background: To investigate a possible role of Cefditoren, a recently marketed in Greece third-generation oral cephalosporin in urinary infections of outpatients.Methods: During a multicenter survey of Enterobacteriaceae ...

Article

Chlamydia pneumoniae infection and the risk of multiple sclerosis: A meta-analysis

Bagos, Pantelis G.; Nikolopoulos, Georgios K.; Ioannidis, A. (2006)

We conducted a meta-analysis of studies comparing the presence of Chlamydia pneumoniae (Cpn) between multiple sclerosis (MS) patients and other neurological diseases patients or healthy controls. We identified 26 studies ...

Article

Comparative study of prognostic value for coronary disease risk between the U.K. prospective diabetes study and Framingham models: Response to Protopsaltis et al. [9] (multiple letters)

Stevens, R. J.; Holman, R.; Protopsaltis, I. D.; Nikolopoulos, Georgios K.; Melidonis, Andreas (2004)

Article

Design and baseline findings of a large-scale rapid response to an HIV outbreak in people who inject drugs in Athens, Greece: The ARISTOTLE programme

Hatzakis, A.; Sypsa, V.; Paraskeva, D.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Micha, Katerina; Panopoulos, A.; Malliori-Minerva, Melpomeni; Psichogiou, M.; Pharris, Anastasia; Wiessing, L.; Laar, M. J. van de; Donoghoe, Martin; Heckathorn, Douglas D.; Friedman, Samuel R.; Jarlais, Don C. Des (2015)

Aims: To (i) describe an intervention implemented in response to the HIV-1 outbreak among people who inject drugs (PWIDs) in Greece (ARISTOTLE programme), (ii) assess its success in identifying and testing this population ...

Article

The diagnosis and management of gastric cancer: Expert discussion and recommendations from the 12th ESMO/World Congress on Gastrointestinal Cancer, Barcelona, 2010

Cutsem, E. van; Dicato, M.; Geva, R.; Arber, N.; Bang, Y.; Benson, A.; Cervantes, A.; Diaz-Rubio, E.; Ducreux, M.; Glynne-Jones, R.; Grothey, Axel; Haller, D.; Haustermans, K.; Kerr, D.; Nordlinger, B.; Marshall, J.; Minsky, B. D.; Kang, Y. K.; Labianca, R.; Lordick, F.; Ohtsu, A.; Pavlidis, Nicholas; Roth, A.; Rougier, P.; Schmoll, H. J.; Sobrero, A.; Tabernero, Josep; Velde, C. van de; Zalcberg, J. (2011)

Well-recognized experts in the field of gastric cancer discussed during the 12th European Society Medical Oncology (ESMO)/World Congress Gastrointestinal Cancer (WCGIC) in Barcelona many important and controversial topics ...

Article

Docetaxel and carboplatin combination chemotherapy as outpatient palliative therapy in carcinoma of unknown primary: A multicentre Hellenic Cooperative Oncology Group phase II study

Pentheroudakis, George; Briassoulis, E. Ch; Kalofonos, H. P.; Fountzilas, George; Economopoulos, T.; Samelis, G.; Koutras, A. K.; Karina, M.; Xiros, N.; Samantas, E.; Bamias, A. T.; Pavlidis, Nicholas (2008)

Introduction. Taxane/platinum combinations exhibit synergistic cytotoxicity and activity against a broad range of solid tumours. We sought to optimise the regimen as a suitable outpatient palliative treatment for cancer ...

Article

Effect of angiotensin converting enzyme gene I/D polymorphism and its expression on clinical outcome in acute respiratory distress syndrome

Tsantes, Argirio E.; Kopterides, Petros; Bonovas, Stefanos; Bagos, Pantelis G.; Antonakos, Georgios; Nikolopoulos, Georgios K.; Gialeraki, Argiri; Kapsimali, Violetta; Kyriakou, Elias; Kokoris, Styliani; Dima, Kleanthi; Armaganidis, Apostolos; Tsangaris, I. (2013)

Background. The role of the D allele of the angiotensin-converting enzyme (ACE) gene I/D polymorphism in the clinical outcomes of patients with acute lung injury and acute respiratory distress syndrome (ALI/ARDS) remains ...

Article

Effect of letrozole on the lipid profile in postmenopausal women with breast cancer

Elisaf, Moses S.; Bairaktari, Eleni Th; Nikolaides, C.; Kakaidi, B.; Tzallas, C. S.; Katsaraki, A.; Pavlidis, Nicholas (2001)

Hormonal therapy plays a central role in the overall treatment of breast cancer. Aromatase inhibitors can inhibit the aromatase enzyme system resulting in a reduction of oestrogens. Letrozole is a non-steroidal aromatase ...

Article

Efficacy and safety of more intensive lowering of LDL cholesterol [1]

Bonovas, Stefanos; Nikolopoulos, Georgios K.; Sitaras, N. M. (2011)

Article

An epidemiological overview of malaria in Bangladesh

Islam, Nazrul; Bonovas, Stefanos; Nikolopoulos, Georgios K. (2013)

Bangladesh is one of the four major malaria-endemic countries in South-East Asia having approximately 34% of its population at risk of malaria. This paper aims at providing an overview of the malaria situation in this ...

Article

Evaluation of thermal discomfort in Athens territory and its effect on the daily number of recorded patients at hospitals' emergency rooms

Pantavou, K. G.; Theoharatos, G.; Nikolopoulos, Georgios K.; Katavoutas, G.; Asimakopoulos, D. (2008)

Previous research has shown that temperature and humidity affect human health. However, only a few studies have examined the association of a biometeorological index, which combines several meteorological parameters and ...

Article

Gene expression of estrogen receptor, progesterone receptor and microtubule-associated protein Tau in high-risk early breast cancer: A quest for molecular predictors of treatment benefit in the context of a Hellenic Cooperative Oncology Group trial

Pentheroudakis, George; Kalogeras, K. T.; Wirtz, R. M.; Grimani, I.; Zografos, G.; Gogas, H.; Stropp, U.; Pectasides, Dimitrios; Skarlos, Dimosthenis V.; Hennig, G.; Samantas, E.; Bafaloukos, Dimitrios; Papakostas, P.; Kalofonos, H. P.; Pavlidis, Nicholas; Fountzilas, George (2009)

Background Estrogen receptor (ER) and progesterone receptor (PgR) protein expression carry weak prognostic and moderate predictive utility for the outcome of early breast cancer patients on adjuvant chemohormonotherapy. ...

Article

Human immunodeficiency virus in injecting drug users in Europe following a reported increase of cases in Greece and Romania, 2011

Pharris, Anastasia; Wiessing, L.; Sfetcu, O.; Hedrich, D.; Botescu, A.; Fotiou, Anastasios; Nikolopoulos, Georgios K.; Malliori-Minerva, Melpomeni; Salminen, M.; Suk, J. E.; Griffiths, P.; Laar, M. J. van de (2011)

Greece and Romania reported an increased number of HIV cases among injecting drug users (IDUs) during 2011. Most European countries reported no changes in the rate of newly diagnosed cases of HIV or HIV prevalence in IDUs; ...

Article

Integrin, alpha 2 gene C807T polymorphism and risk of ischemic stroke: A meta-analysis

Nikolopoulos, Georgios K.; Tsantes, Argirio E.; Bagos, Pantelis G.; Travlou, Anthi S.; Vaiopoulos, G. (2007)

Introduction: Platelet adhesion to fibrillar collagen via the membrane glycoprotein (GP) Ia/IIa (α2β1), is a crucial event in the pathogenesis of arterial occlusive disorders. The C807T single nucleotide polymorphism of ...

Article

Lack of association between the platelet glycoprotein Ia C807T gene polymorphism and coronary artery disease: A meta-analysis

Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Vaiopoulos, G.; Travlou, Anthi S. (2007)

Background: The platelet-collagen receptor, glycoprotein (GP) la/lla plays a crucial role in the adhesion of platelets to fibrillar collagen, an event contributing to the pathogenesis of thrombosis. The C807T polymorphism ...

Article

Late toxicity in survivors from adolescent cancers

Pentheroudakis, George; Pavlidis, Nicholas (2007)

Nowadays three quarters of adolescents with cancer are cured but half of them experience a late toxic effect of antineoplastic therapy that interferes with their physical and psychosocial health. This review recapitulates ...

Article

Low-grade mucosa-associated lymphoid tissue lymphoma: A retrospective analysis of 97 patients by the Hellenic Cooperative Oncology Group (HeCOG)

Papaxoinis, G.; Fountzilas, George; Rontogianni, D.; Dimopoulos, M. A.; Pavlidis, Nicholas; Tsatalas, C.; Pectasides, Dimitrios; Xiros, N.; Economopoulos, T. (2008)

Background: The aim was to examine characteristics and treatment results of patients with mucosa-associated lymphoid tissue (MALT) non-Hodgkin's lymphomas. Patients and methods: Epidemiological and clinical features of 97 ...