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Browsing by Subject "epidermis"

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    • Article  

      Direct conversion of mouse embryonic fibroblasts into functional keratinocytes through transient expression of pluripotency-related genes 

      Iacovides, D.; Rizki, G.; Lapathitis, Georgios; Strati, K. (2016)
      The insufficient ability of specialized cells such as neurons, cardiac myocytes, and epidermal cells to regenerate after tissue damage poses a great challenge to treat devastating injuries and ailments. Recent studies ...

    • Article  

      Evidence that a metabolilte of equine estrogens, 4-hydroxyequilenin, induces cellular transformation in vitro 

      Pisha, E.; Lui, X.; Constantinou, Andreas I.; Bolton, J. L. (2001)
      Estrogen replacement therapy has been correlated with an increased risk of developing hormone-dependent cancers. 4-Hydroxyequilenin (4-OHEN) is a catechol metabolite of equilenin and equilin which are components of the ...

    • Article  

      The mouse Foxi3 transcription factor is necessary for the development of posterior placodes 

      Birol, O.; Ohyama, T.; Edlund, R. K.; Drakou, Katerina; Georgiades, Pantelis; Groves, A. K. (2016)
      The inner ear develops from the otic placode, one of the cranial placodes that arise from a region of ectoderm adjacent to the anterior neural plate called the pre-placodal domain. We have identified a Forkhead family ...

    • Article  

      Tissue communication in regenerative inflammatory signaling: Lessons from the fly gut 

      Kux, K.; Pitsouli, Chrysoula (2014)
      The intestine, as a barrier epithelium, serves in the first line of defense against invading pathogens and damaging agents that enter the body via food ingestion. Maintenance of intestinal homeostasis is therefore key to ...

    • Article  

      Xenopus laevis nucleotide binding protein 1 (xNubp1) is important for convergent extension movements and controls ciliogenesis via regulation of the actin cytoskeleton 

      Ioannou, Androulla; Santama, Niovi; Skourides, Paris A. (2013)
      Nucleotide binding protein 1 (Nubp1) is a highly conserved phosphate loop (P-loop) ATPase involved in diverse processes including iron-sulfur protein assembly, centrosome duplication and lung development. Here, we report ...

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