Browsing by Subject "mouse mutant"

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    • Article  

      The mouse Foxi3 transcription factor is necessary for the development of posterior placodes 

      Birol, O.; Ohyama, T.; Edlund, R. K.; Drakou, Katerina; Georgiades, Pantelis; Groves, A. K. (2016)
      The inner ear develops from the otic placode, one of the cranial placodes that arise from a region of ectoderm adjacent to the anterior neural plate called the pre-placodal domain. We have identified a Forkhead family ...
    • Article  

      Trophoblast-specific gene manipulation using lentivirus-based vectors 

      Georgiades, Pantelis; Cox, B.; Gertsenstein, M.; Chawengsaksophak, K.; Rossant, J. (2007)
      The trophoblast layers of the mammalian placenta carry out many complex functions required to pattern the developing embryo and maintain its growth and survival in the uterine environment. Genetic disruption of many gene ...